Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | PRKACA | P17612 | 1/20 | 0.38 |
| ▸ | PRKACG | P22612 | 1/20 | 0.38 |
| ▸ | PRKACB | P22694 | 1/20 | 0.38 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28043072 | 0.84 | — | — | |
| SCHEMBL28185057 | 0.81 | HTR1A (0.43) | SCN5ANISCH | |
| SCHEMBL16004999 | 0.80 | SCN5A (0.49) | KDM1AMAOBTRPA1SCN5ASCN9A | |
| SCHEMBL28042881 | 0.73 | ABL1 (0.49) | SCN9A | |
| SCHEMBL28043076 | 0.70 | HTR1A (0.46) | — | |
| SCHEMBL16014446 | 0.69 | GALR2 (0.46) | TRPA1SCN5ASCN9A | |
| SCHEMBL2959126 | 0.68 | PRKACA (0.44) | PRKACAPRKACGPRKACB | |
| SCHEMBL894210 | 0.67 | SCN10A (0.46) | KDM1AMAOBTRPA1SCN5ASCN9A | |
| SCHEMBL30403295 | 0.66 | HTR1A (0.65) | PRKACAPRKACGPRKACB | |
| SCHEMBL5547294 | 0.66 | HTR1A (0.65) | PRKACAPRKACGPRKACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105143188-A | Novel sulfonamide trpa1 receptor antagonists | PHARMESTE S R L IN LIQUIDATION | 2015-12-09 | — | — | CN | disclosed |