Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28043072 | 0.86 | — | — | |
| SCHEMBL27988602 | 0.71 | SLC6A3 (0.46) | — | |
| SCHEMBL26249383 | 0.71 | TP53 (0.43) | HTR1A | |
| SCHEMBL26249388 | 0.71 | TP53 (0.43) | HTR1A | |
| SCHEMBL26249385 | 0.71 | TP53 (0.43) | HTR1A | |
| SCHEMBL17224083 | 0.70 | — | — | |
| SCHEMBL17224109 | 0.70 | — | — | |
| SCHEMBL17224076 | 0.70 | — | — | |
| SCHEMBL28042882 | 0.70 | KDM1A (0.39) | — | |
| SCHEMBL1760973 | 0.70 | HTR1A (0.68) | HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105143188-A | Novel sulfonamide trpa1 receptor antagonists | PHARMESTE S R L IN LIQUIDATION | 2015-12-09 | — | — | CN | disclosed |