Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 1/20 | 0.55 |
| ▸ | KIF11 | P52732 | 6/20 | 0.53 |
| ▸ | XDH | P47989 | 1/20 | 0.44 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.44 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 2/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.40 |
| ▸ | SYK | P43405 | 1/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.39 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.39 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.39 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1934836 | 0.84 | CTSS (0.60) | MYCCTSSSYKCTSK | |
| SCHEMBL17116601 | 0.82 | MYC (0.65) | MYCXDHABCG2NPY5R | |
| SCHEMBL31133396 | 0.82 | MYC (0.62) | MYCXDHABCG2NPY5R | |
| SCHEMBL9792895 | 0.82 | MYC (0.62) | MYCXDHABCG2NPY5R | |
| SCHEMBL16635603 | 0.81 | CTSS (0.43) | MYCKIF11XDHABCG2DGAT1 | |
| SCHEMBL2952766 | 0.81 | MYC (0.59) | MYCXDHABCG2NPY5RCYP2D6 | |
| SCHEMBL18224145 | 0.81 | MYC (0.52) | MYCXDHABCG2 | |
| SCHEMBL16894249 | 0.81 | MYC (0.49) | MYCXDHABCG2DGAT1SYK | |
| SCHEMBL2334808 | 0.80 | NOS3 (0.52) | MYCKIF11XDHABCG2DGAT1 | |
| SCHEMBL29775960 | 0.80 | NOS3 (0.52) | MYCKIF11XDHABCG2DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105143188-A | Novel sulfonamide trpa1 receptor antagonists | PHARMESTE S R L IN LIQUIDATION | 2015-12-09 | — | — | CN | disclosed |