Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20774866 | 0.84 | P2RX7 (0.31) | P2RX7 | |
| SCHEMBL27562253 | 0.73 | MEN1 (0.44) | — | |
| SCHEMBL27996912 | 0.71 | BACE1 (0.46) | — | |
| SCHEMBL27996600 | 0.69 | LPAR1 (0.42) | LMNA | |
| SCHEMBL31710662 | 0.69 | KMT2A (0.40) | LMNA | |
| SCHEMBL28038250 | 0.68 | ALDH1A1 (0.37) | — | |
| SCHEMBL6213840 | 0.68 | KDM4E (0.35) | LMNA | |
| SCHEMBL27919020 | 0.67 | KDM4E (0.36) | — | |
| SCHEMBL16177237 | 0.67 | CNR2 (0.46) | LMNA | |
| SCHEMBL16177346 | 0.65 | ALDH1A1 (0.41) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105143203-A | N-piperidin-3-ylbenzamide derivatives for the treatment of cardiovascular diseases | PFIZER | 2015-12-09 | — | — | CN | disclosed |