Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 1/20 | 0.61 |
| ▸ | CA12 | O43570 | 3/20 | 0.57 |
| ▸ | CA4 | P22748 | 3/20 | 0.57 |
| ▸ | CA6 | P23280 | 3/20 | 0.57 |
| ▸ | CA5A | P35218 | 3/20 | 0.57 |
| ▸ | CA7 | P43166 | 3/20 | 0.57 |
| ▸ | CA9 | Q16790 | 3/20 | 0.57 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.57 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.57 |
| ▸ | CA1 | P00915 | 2/20 | 0.57 |
| ▸ | DRD2 | P14416 | 1/20 | 0.55 |
| ▸ | DRD1 | P21728 | 1/20 | 0.55 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.51 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.51 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.48 |
| ▸ | SPR | P35270 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3878665 | 0.83 | LMNA (0.53) | TYRCA12CA4CA6CA5A | |
| SCHEMBL27608519 | 0.83 | TYR (0.61) | TYRCA12CA4CA6CA5A | |
| SCHEMBL28321491 | 0.81 | TAAR1 (0.53) | TAAR1LMNACHRM1IDO1 | |
| SCHEMBL16244166 | 0.81 | TAAR1 (0.53) | TAAR1LMNAIDO1 | |
| SCHEMBL16244351 | 0.81 | HTR3E (0.54) | TAAR1LMNAIDO1 | |
| SCHEMBL14432434 | 0.81 | TAAR1 (0.53) | TAAR1LMNACHRM1IDO1 | |
| Phenylethyl Carbamate SCHEMBL111316 | 0.80 | LMNA (0.79) | CA9CA1LMNAAKR1B10AKR1B1 | |
| SCHEMBL1119161 | 0.79 | CA12 (0.64) | TYRCA12CA4CA6CA5A | |
| SCHEMBL16244900 | 0.79 | TAAR1 (0.58) | TAAR1CHRM2CHRM1CHRM3IDO1 | |
| SCHEMBL31744993 | 0.79 | CA12 (0.64) | TYRCA12CA4CA6CA5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115477634-B | Analgesic compounds and medical uses thereof | 中国人民解放军军事科学院军事医学研究院 | 2024-02-13 | — | — | CN | disclosed |
| CN-116981672-A | Macrocyclic compounds as CFTR modulators | 爱杜西亚药品有限公司 | 2023-10-31 | — | — | CN | disclosed |
| CN-115477634-A | Compound for analgesia and medical application thereof | 中国人民解放军军事科学院军事医学研究院 | 2022-12-16 | — | — | CN | disclosed |
| CN-105142673-B | Novel cyclohexyl and quininuclidinyl carbamate derivatives with beta 2-adrenergic activator and M3 muscarinic antagonists activity | 阿尔米雷尔有限公司 | 2018-01-05 | — | — | CN | disclosed |
| CN-105142673-A | New cyclohexyl and quinuclidinyl carbamate derivatives having beta2 adrenergic agonist and M3 muscarinic antagonist activity | ALMIRALL SA | 2015-12-09 | — | — | CN | disclosed |