Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.42 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.42 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.42 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.41 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4341894 | 0.83 | NOTUM (0.78) | NOTUMKDM4EALDH1A1MAPK1DRD2 | |
| SCHEMBL11117073 | 0.81 | NOTUM (0.58) | NOTUMKDM4EALDH1A1MAPK1MAPT | |
| SCHEMBL28205331 | 0.81 | NOTUM (0.58) | NOTUMKDM4EALDH1A1MAPK1DRD2 | |
| Hydrochloric Acid SCHEMBL3878758 | 0.79 | NOTUM (0.56) | NOTUMKDM4EALDH1A1MAPK1DRD2 | |
| SCHEMBL182132 | 0.78 | NOTUM (1.00) | NOTUMKDM4EALDH1A1MAPK1DRD2 | |
| SCHEMBL12882840 | 0.77 | ALDH1A1 (0.62) | NOTUMKDM4EALDH1A1MAPK1MAPT | |
| SCHEMBL13123487 | 0.77 | NOTUM (0.53) | NOTUMKDM4EALDH1A1MAPK1DRD2 | |
| SCHEMBL173885 | 0.75 | NOTUM (0.67) | NOTUMKDM4EALDH1A1MAPK1DRD2 | |
| SCHEMBL10310334 | 0.75 | NOTUM (0.51) | NOTUMKDM4EALDH1A1MAPK1MAPT | |
| SCHEMBL27250 | 0.74 | NOTUM (0.65) | NOTUMKDM4EALDH1A1MAPK1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105051033-A | Antiviral compounds | HOFFMANN LA ROCHE | 2015-11-11 | — | — | CN | disclosed |