Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.49 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.47 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.46 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.45 |
| ▸ | PPARG | P37231 | 7/20 | 0.45 |
| ▸ | PPARD | Q03181 | 7/20 | 0.45 |
| ▸ | PPARA | Q07869 | 7/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.45 |
| ▸ | TSHR | P16473 | 4/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | TLR2 | O60603 | 2/20 | 0.45 |
| ▸ | FABP4 | P15090 | 2/20 | 0.45 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.45 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Stearic Acid SCHEMBL27732488 | 0.91 | FFAR4 (0.61) | ALDH1A1FFAR4FFAR1AKR1B1CPB2 | |
| Octanoic Acid SCHEMBL29070665 | 0.91 | FFAR4 (0.61) | ALDH1A1FFAR4FFAR1AKR1B1CPB2 | |
| SCHEMBL7717443 | 0.91 | FFAR4 (0.61) | ALDH1A1FFAR4FFAR1AKR1B1CPB2 | |
| Dodecanoate SCHEMBL28889306 | 0.90 | FFAR4 (0.59) | ALDH1A1FFAR4FFAR1AKR1B1GPR84 | |
| SCHEMBL6458256 | 0.87 | AKR1B1 (0.48) | ALDH1A1FFAR4FFAR1AKR1B1GPR84 | |
| SCHEMBL8744261 | 0.86 | CPB2 (0.50) | ALDH1A1FFAR4FFAR1CPB2GPR84 | |
| SCHEMBL14809348 | 0.86 | CPB2 (0.50) | ALDH1A1FFAR4FFAR1CPB2GPR84 | |
| SCHEMBL14809034 | 0.86 | CPB2 (0.50) | ALDH1A1FFAR4FFAR1CPB2GPR84 | |
| SCHEMBL14809730 | 0.86 | CPB2 (0.50) | ALDH1A1FFAR4FFAR1CPB2GPR84 | |
| SCHEMBL14810123 | 0.86 | CPB2 (0.50) | ALDH1A1FFAR4FFAR1CPB2GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105348185-B | Bicyclic [3.2.1] octyl group amide derivatives and application thereof | H.隆德贝克有限公司 | 2018-02-16 | — | — | CN | disclosed |
| CN-105348185-A | Bicyclo[3.2.1]octyl amide derivatives and uses of same | LUNDBECK & CO AS H | 2016-02-24 | — | — | CN | disclosed |
| CN-103369961-B | Bicyclo [3.2.1] octylamide derivatives and uses thereof | H. LUNDBECK A/S (DK) | 2015-11-25 | — | — | CN | disclosed |