Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.47 |
| ▸ | PPARG | P37231 | 7/20 | 0.47 |
| ▸ | PPARD | Q03181 | 7/20 | 0.47 |
| ▸ | PPARA | Q07869 | 7/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.47 |
| ▸ | TSHR | P16473 | 4/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | TLR2 | O60603 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | FABP4 | P15090 | 2/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.47 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.47 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dodecanoate SCHEMBL28889306 | 0.91 | FFAR4 (0.59) | AKR1B1GPR84PPARGPPARDPPARA | |
| Octanoic Acid SCHEMBL29070665 | 0.89 | FFAR4 (0.61) | AKR1B1GPR84PPARGPPARDPPARA | |
| SCHEMBL7717443 | 0.89 | FFAR4 (0.61) | AKR1B1GPR84PPARGPPARDPPARA | |
| Stearic Acid SCHEMBL27732488 | 0.89 | FFAR4 (0.61) | AKR1B1GPR84PPARGPPARDPPARA | |
| SCHEMBL5491480 | 0.88 | CA2 (0.57) | CA2CA1MAPK1TSHRALDH1A1 | |
| SCHEMBL6935643 | 0.87 | AKR1B1 (0.47) | AKR1B1CA2CA1MAPK1GPR84 | |
| SCHEMBL28042973 | 0.87 | ALDH1A1 (0.51) | AKR1B1GPR84PPARGPPARDPPARA | |
| SCHEMBL4113412 | 0.87 | CA2 (0.48) | AKR1B1CA2CA1MAPK1GPR84 | |
| SCHEMBL21052329 | 0.86 | CA2 (0.55) | CA2CA1MAPK1TSHRALDH1A1 | |
| Hydrochloric Acid SCHEMBL27486062 | 0.86 | CA2 (0.55) | CA2CA1MAPK1TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1513848-A4 | METHOD OF TREATING ISCHEMIA REPERFUSION INJURY USING ADENOSINE RECEPTOR ANTAGONISTS | BIOGEN IDEC INC (US) | 2005-11-09 | — | — | EP | disclosed |
| EP-1513848-A2 | METHOD OF TREATING ISCHEMIA REPERFUSION INJURY USING ADENOSINE RECEPTOR ANTAGONISTS | Biogen Idec MA Inc. (US) | 2005-03-16 | — | — | EP | disclosed |
| WO-2003105666-A2 | METHOD OF TREATING ISCHEMIA REPERFUSION INJURY USING ADENOSINE RECEPTOR ANTAGONISTS | BIOGEN, INC. (US) | 2003-12-24 | — | — | WO | disclosed |