Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 12/20 | 0.41 |
| ▸ | CA1 | P00915 | 11/20 | 0.41 |
| ▸ | CA9 | Q16790 | 8/20 | 0.41 |
| ▸ | CA6 | P23280 | 3/20 | 0.41 |
| ▸ | CA5A | P35218 | 3/20 | 0.41 |
| ▸ | CA12 | O43570 | 3/20 | 0.41 |
| ▸ | CA4 | P22748 | 2/20 | 0.41 |
| ▸ | CA7 | P43166 | 2/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | GBA1 | P04062 | 1/20 | 0.38 |
| ▸ | LDHA | P00338 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2588715 | 0.81 | CA2 (0.43) | CA2CA1CA9CA6CA5A | |
| SCHEMBL28043283 | 0.78 | — | — | |
| SCHEMBL3284628 | 0.74 | HTR2A (0.48) | CA2CA1CA9CA6CA5A | |
| SCHEMBL16371920 | 0.72 | CES2 (0.43) | HRH1 | |
| SCHEMBL28261014 | 0.70 | PTGES2 (0.47) | CA2CA1CA9CA6CA5A | |
| SCHEMBL9524316 | 0.70 | CA1 (0.42) | CA2CA1CA9CA6CA5A | |
| SCHEMBL17760496 | 0.70 | CA2 (0.40) | CA2CA1CA9CA6CA5A | |
| SCHEMBL29933194 | 0.70 | CA2 (0.50) | CA2CA1CA9CA6CA5A | |
| SCHEMBL1106519 | 0.70 | CA1 (0.53) | CA2CA1CA9CA6CA5A | |
| SCHEMBL21826752 | 0.70 | CA2 (0.50) | CA2CA1CA9CA6CA5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102197023-B | Compounds for the treatment of ophthalmic diseases and disorders | ACUCELA INC. (US) | 2015-12-16 | — | — | CN | disclosed |