SCHEMBL28043124

SCHEMBL28043124

O=CC=CCc1cccc(-c2ccccc2)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AGXT P21549 2/20 0.49
MAOB P27338 1/20 0.43
PTGS2 P35354 1/20 0.41
GPR52 Q9Y2T5 1/20 0.41
AOC3 Q16853 3/20 0.41
GGPS1 O95749 2/20 0.41
GPR84 Q9NQS5 1/20 0.40
BCL2 P10415 1/20 0.39
CCNB2 O95067 1/20 0.39
CDK1 P06493 1/20 0.39
CDK4 P11802 1/20 0.39
CCNB1 P14635 1/20 0.39
CCND1 P24385 1/20 0.39
CCNB3 Q8WWL7 1/20 0.39
FAAH O00519 1/20 0.38
NAAA Q02083 1/20 0.38
NR4A2 P43354 1/20 0.38
HRH3 Q9Y5N1 1/20 0.37
CYP11B1 P15538 1/20 0.37
CYP11B2 P19099 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1420024 0.83 AGXT (0.52) AGXTPTGS2GPR52AOC3GGPS1
SCHEMBL3132480 0.82 MAOB (0.64) MAOBCCNB2CDK1CDK4CCNB1
SCHEMBL145089 0.82 MAOB (0.64) MAOBCCNB2CDK1CDK4CCNB1
SCHEMBL12809833 0.82 MAOB (0.64) MAOBCCNB2CDK1CDK4CCNB1
SCHEMBL2586836 0.78 AGXT (0.45) AGXTPTGS2GPR52AOC3GGPS1
SCHEMBL6686708 0.78 MAPT (0.47) MAOBPTGS2CCNB2CDK1CDK4
SCHEMBL27486985 0.78 AGXT (0.56) AGXTMAOBPTGS2GPR52AOC3
SCHEMBL29018928 0.77 AOC3 (0.51) AGXTMAOBPTGS2GPR52AOC3
SCHEMBL1348922 0.76 IDO1 (0.47) MAOBGPR52GPR84HRH3
SCHEMBL2796485 0.76 IDO1 (0.47) AGXTMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105152896-A Method for preparing 1, 4-diphenyl-2-benzophenone UNIV ZHEJIANG TECHNOLOGY 2015-12-16 CN claimed
CN-105152896-A Method for preparing 1, 4-diphenyl-2-benzophenone UNIV ZHEJIANG TECHNOLOGY 2015-12-16 CN disclosed