SCHEMBL145089

SCHEMBL145089

O=CC=CCc1ccccc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.64
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
ARG2 P78540 1/20 0.48
MAPK1 P28482 2/20 0.44
TRPA1 O75762 1/20 0.44
ALDH1A1 P00352 1/20 0.44
LMNA P02545 1/20 0.44
ALOX5 P09917 1/20 0.44
TOP1 P11387 1/20 0.44
CCNB2 O95067 2/20 0.43
CDK1 P06493 2/20 0.43
CDK4 P11802 2/20 0.43
CCNB1 P14635 2/20 0.43
CCND1 P24385 2/20 0.43
CCNB3 Q8WWL7 2/20 0.43
ADH1B P00325 1/20 0.41
ADH1C P00326 1/20 0.41
ADH1A P07327 1/20 0.41
ADH7 P40394 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3132480 1.00 MAOB (0.64) MAOBCA1CA2ARG2MAPK1
SCHEMBL12809833 1.00 MAOB (0.64) MAOBCA1CA2ARG2MAPK1
SCHEMBL8348918 0.91 MAOB (0.58) MAOBCA1CA2ARG2MAPK1
SCHEMBL6803904 0.91 MAOB (0.58) MAOBCA1CA2ARG2MAPK1
SCHEMBL462351 0.85 MAOB (0.78) MAOBCA1CA2ARG2MAPK1
SCHEMBL628859 0.85 MAOB (0.78) MAOBCA1CA2ARG2MAPK1
SCHEMBL28043124 0.82 AGXT (0.49) MAOBCCNB2CDK1CDK4CCNB1
SCHEMBL27558493 0.82 MAOB (0.74) MAOBCA1CA2ARG2MAPK1
SCHEMBL30075910 0.82 MAOB (0.74) MAOBCA1CA2ARG2MAPK1
SCHEMBL95697 0.79 MAOB (0.61) MAOBCA1CA2ARG2MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 856 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3017000-B1 PHENOLIC POLYSULPHIDES HAVING AN IMPROVED ODOUR ARKEMA FRANCE (FR) 2024-05-29 EP claimed
CN-117447334-A Method for efficiently synthesizing alpha-amino acetal 南京工业大学 2024-01-26 CN claimed
CN-115460933-A Flavour composition for improving taste impression 西姆莱斯有限公司 2022-12-09 CN claimed
CN-108651471-A A kind of preparation method of timber sterilization antiseptic 长乐智高生物科技有限公司 2018-10-16 CN claimed
EP-2847318-A1 PESTICIDAL FLAVOBACTERIUM STRAIN AND BIOACTIVE COMPOSITIONS, METABOLITES AND USES Marrone Bio Innovations, Inc. (US) 2015-03-18 EP claimed
US-20150031534-A1 PESTICIDAL FLAVOBACTERIUM STRAIN AND BIOACTIVE COMPOSITIONS METABOLITES AND USES PRO FARM GROUP, INC. 2015-01-29 US claimed
WO-2013138398-A1 PESTICIDAL FLAVOBACTERIUM STRAIN AND BIOACTIVE COMPOSITIONS, METABOLITES AND USES MARRONE BIO INNOVATIONS, INC. (US) 2013-09-19 WO claimed
CN-101462947-B Preparation of (R) -4-phenyl-2-hydroxybutyrate SHANGHAI BAIDING PHARMACEUTICAL TECHNOLOGY CO LTD 2012-07-25 CN claimed
EP-2411004-A1 USE OF ANDROGRAPHOLIDE COMPOUNDS FOR TREATING INFLAMMATION AND AIRWAY DISORDERS National University of Singapore (SG) 2012-02-01 EP claimed
US-20120015923-A1 USE OF ANDROGRAPHOLIDE COMPOUNDS FOR TREATING INFLAMMATION AND AIRWAY DISORDERS NATIONAL UNIVERSITY OF SINGAPORE (SG) 2012-01-19 US claimed
WO-2010110748-A1 USE OF ANDROGRAPHOLIDE COMPOUNDS FOR TREATING INFLAMMATION AND AIRWAY DISORDERS NATIONAL UNIVERSITY OF SINGAPORE (SG) 2010-09-30 WO claimed
CN-101462947-A Preparation of (R) -4-phenyl-2-hydroxybutyrate SHANGHAI BAIDING PHARMACEUTICA (CN) 2009-06-24 CN claimed
US-7375081-B2 Therapeutic combination of a pneumocandin derivative and an antifungal agent ASTELLAS PHARMA INC. (JP) 2008-05-20 US claimed
US-6875740-B1 Combination of a cyclic hexapeptide with antifungal drugs for treatment of fungal pathogens FUJISAWA PHARMACEUTICAL CO. LTD. (JP) 2005-04-05 US claimed
US-5302608-A Antidiabetic, anticholesterol agents; vision disorders TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1994-04-12 US claimed
US-4861815-A BLENDS BAYER AKTEINGESELLSCHAFT (DE) 1989-08-29 US claimed
CN-120076993-A Aerosol dispenser and nozzle 宝洁公司 2025-05-30 CN disclosed
US-12220677-B2 Process for the preparation of microcapsules SYMRISE AG (DE) 2025-02-11 US disclosed
US-4410730-A Process for the production of o-(N-monosubstituted amino)benzyl alcohols SHIONOGI & CO., LTD. (JP) 1983-10-18 US disclosed
US-4073813-A PLATINUM REDUCTION CATALYST, ALDEHYDES, HYDROGEN RHONE-POULENC INDUSTRIES (FR) 1978-02-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120015923-A1 USE OF ANDROGRAPHOLIDE COMPOUNDS FOR TREATING INFLAMMATION AND AIRWAY DISORDERS NFKBIA, CCL11, IL5 MAOB 2649/4885CA1 3534/4885CA2 2983/4885
US-20150031534-A1 PESTICIDAL FLAVOBACTERIUM STRAIN AND BIOACTIVE COMPOSITIONS METABOLITES AND USES BLVRB, PRDX6, ACHE MAOB 224/4885CA1 4277/4885CA2 3385/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.