Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 4/20 | 0.40 |
| ▸ | F2 | P00734 | 2/20 | 0.40 |
| ▸ | PLAU | P00749 | 2/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27344743 | 0.90 | ALDH1A1 (0.47) | CYP11B1CYP11B2ALDH1A1CYP1A2CYP2C19 | |
| Hydrochloric Acid SCHEMBL27804686 | 0.89 | ALDH1A1 (0.45) | CYP11B1CYP11B2ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL23782714 | 0.78 | ELANE (0.49) | ELANEF2PLAUCYP11B1CYP11B2 | |
| SCHEMBL1969701 | 0.78 | ELANE (0.49) | ELANEF2PLAUALDH1A1CYP1A2 | |
| SCHEMBL8725002 | 0.74 | MAPT (0.50) | ALDH1A1KMT2AKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL4433081 | 0.71 | KDM4E (0.50) | ELANEF2PLAUALDH1A1KDM4E | |
| SCHEMBL29162356 | 0.71 | GLS (0.47) | ELANEF2PLAUCYP11B1CYP11B2 | |
| SCHEMBL7737863 | 0.71 | CNR1 (0.51) | CYP11B1CYP11B2ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL27834342 | 0.70 | KHK (0.57) | CYP11B1CYP11B2ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL6852832 | 0.70 | ELANE (0.53) | ELANEF2PLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105078993-A | Indazole compound composition and preparation method and application thereof | ZHEJIANG DAGUO BIOMEDICINE TECHNOLOGY CO LTD | 2015-11-25 | — | — | CN | disclosed |