Known targets — ChEMBL curated mechanism
ABL1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB2AGTR1BCL2BCL2A1BCL2L1BCL2L10BCL2L2BCRBRAFCHRM1CHRNA10CHRNA9DRD1DRD2DRD3DRD4DRD5EGFRF2FLT1FLT4GCKGHSRGNRHRGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHTR1AHTR1BHTR1DHTR2AHTR2CHTR3AIDH2KDRKITMAOBMCL1MTTPPP4HBPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PIKFYVEROCK1ROCK2SLC18A2SLC6A2SLC6A3SLC6A4TACR1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8gyrAgyrBparCparEpol
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GUSB | P08236 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | EBP | Q15125 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 2/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.33 |
| ▸ | MGLL | Q99685 | 2/20 | 0.33 |
| ▸ | GBA1 | P04062 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | MMP7 | P09237 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28043320 | 1.00 | GUSB (0.39) | GUSBCA1CA2EBPSIGMAR1 | |
| SCHEMBL27899709 | 1.00 | GUSB (0.39) | GUSBCA1CA2EBPSIGMAR1 | |
| SCHEMBL27876124 | 1.00 | GUSB (0.39) | GUSBCA1CA2EBPSIGMAR1 | |
| SCHEMBL28315520 | 1.00 | GUSB (0.39) | GUSBCA1CA2EBPSIGMAR1 | |
| Sulfuric Acid SCHEMBL28409224 | 0.95 | GUSB (0.40) | GUSBCA1CA2EBPSIGMAR1 | |
| Sulfuric Acid SCHEMBL28720206 | 0.95 | GUSB (0.40) | GUSBCA1CA2EBPSIGMAR1 | |
| Sulfuric Acid SCHEMBL28761880 | 0.95 | GUSB (0.40) | GUSBCA1CA2EBPSIGMAR1 | |
| Sulfuric Acid SCHEMBL28201495 | 0.95 | GUSB (0.40) | GUSBCA1CA2EBPSIGMAR1 | |
| Sulfuric Acid SCHEMBL27988516 | 0.95 | GUSB (0.40) | GUSBCA1CA2EBPSIGMAR1 | |
| Sulfuric Acid SCHEMBL27874219 | 0.95 | GUSB (0.40) | GUSBCA1CA2EBPSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109860392-A | A kind of organic solar batteries and preparation method thereof using functionalization graphene quantum dot as electron transfer layer | 桂林电子科技大学 | 2019-06-07 | — | — | CN | disclosed |
| CN-109415452-A | The method for preparing highly reactive isobutylene homo or copolymer | 巴斯夫欧洲公司 | 2019-03-01 | — | — | CN | disclosed |
| CN-105633284-B | Make trans- organic solar batteries and the preparation of middle layer using Ionic Liquid Films | 中国科学院大连化学物理研究所 | 2018-07-20 | — | — | CN | disclosed |
| CN-105633284-A | Trans-organic solar cell with ionic liquid film as intermediate layer thereof, and process of preparing trans-organic solar cell | DALIAN INST CHEMICAL PHYSICS CAS | 2016-06-01 | — | — | CN | disclosed |
| CN-105024014-A | Organic solar cell adopting ionic liquid film as interlayer | DALIAN CHEMICAL PHYSICS INST | 2015-11-04 | — | — | CN | disclosed |