Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 5/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LDHA | P00338 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL175616 | 1.00 | — | — | |
| Bicarbonate SCHEMBL7631660 | 1.00 | — | — | |
| Bicarbonate SCHEMBL5680462 | 1.00 | — | — | |
| Bicarbonate SCHEMBL3037570 | 1.00 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL28586227 | 1.00 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL17746828 | 1.00 | — | — | |
| Bicarbonate SCHEMBL3976963 | 1.00 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL14563714 | 0.94 | CA4 (0.42) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL5557766 | 0.94 | — | — | |
| Bicarbonate SCHEMBL10788717 | 0.94 | CA4 (0.42) | CA4CA1FAHD1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113498877-B | Cooling filter stick for heating non-combustible cigarettes and preparation method thereof | 云南氪莱铂科技有限公司 | 2024-05-28 | — | — | CN | claimed |
| CN-113498877-A | Cooling filter rod for heating non-combustible cigarettes and preparation method thereof | 云南氪莱铂科技有限公司 | 2021-10-15 | — | — | CN | claimed |
| CN-119176577-A | Glycerol-stable amorphous calcium carbonate and preparation method and application thereof | 武汉理工大学三亚科教创新园 | 2024-12-24 | — | — | CN | disclosed |
| CN-113498877-B | Cooling filter stick for heating non-combustible cigarettes and preparation method thereof | 云南氪莱铂科技有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-117963967-A | Method for extracting amorphous calcium carbonate from ocean and application thereof | 闽江学院 | 2024-05-03 | — | — | CN | disclosed |
| CN-114907036-A | Calcium carbonate gel, preparation method and application | 武汉大学 | 2022-08-16 | — | — | CN | disclosed |
| CN-113498877-A | Cooling filter rod for heating non-combustible cigarettes and preparation method thereof | 云南氪莱铂科技有限公司 | 2021-10-15 | — | — | CN | disclosed |
| CN-112174181-A | Pumpkin-shaped vaterite-type calcium carbonate and preparation method thereof | 成都理工大学 | 2021-01-05 | — | — | CN | disclosed |
| CN-111892076-A | Preparation method for obtaining amorphous calcium carbonate particles with nano-pore structure by organic solvent induction | 武汉理工大学 | 2020-11-06 | — | — | CN | disclosed |
| CN-105524559-A | Gypsum adhesive | XI'AN ZEHUA BUILDING DECORATION ENG CO LTD | 2016-04-27 | — | — | CN | disclosed |
| CN-204865501-U | Calcium carbonate calcium hydrate - gypsum wet flue gas desulfurization dust collector | UNIV SHENYANG CHEMICAL TECH | 2015-12-16 | — | — | CN | disclosed |
| CN-204865501-U | Calcium carbonate calcium hydrate - gypsum wet flue gas desulfurization dust collector | UNIV SHENYANG CHEMICAL TECH | 2015-12-16 | — | — | CN | disclosed |