Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 5/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LDHA | P00338 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL175616 | 1.00 | — | — | |
| Bicarbonate SCHEMBL7631660 | 1.00 | — | — | |
| Bicarbonate SCHEMBL5680462 | 1.00 | — | — | |
| Bicarbonate SCHEMBL28586227 | 1.00 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL17746828 | 1.00 | — | — | |
| Bicarbonate SCHEMBL28043173 | 1.00 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL3976963 | 1.00 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL14563714 | 0.94 | CA4 (0.42) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL5557766 | 0.94 | — | — | |
| Bicarbonate SCHEMBL10788717 | 0.94 | CA4 (0.42) | CA4CA1FAHD1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 128 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119607491-A | Battery fire extinguishing agent and preparation method and application thereof | 深圳普瑞赛思检测科技股份有限公司 | 2025-03-14 | — | — | CN | claimed |
| WO-2021257757-A1 | CARBONATABLE COMPOSITIONS WITH ADMIXTURES | SOLIDIA TECHNOLOGIES, INC. (US) | 2021-12-23 | — | — | WO | claimed |
| CN-111892076-A | Preparation method for obtaining amorphous calcium carbonate particles with nano-pore structure by organic solvent induction | 武汉理工大学 | 2020-11-06 | — | — | CN | claimed |
| US-9105780-B2 | Method of fabricating graphene quantum dots and high quality graphene quantum dots using the method | KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2015-08-11 | — | — | US | claimed |
| US-20150118143-A1 | METHOD OF FABRICATING GRAPHENE QUANTUM DOTS AND HIGH QUALITY GRAPHENE QUANTUM DOTS USING THE METHOD | KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2015-04-30 | — | — | US | claimed |
| US-5220875-A | Reacting sulfur dioxide with calcined sorbent in presence of oxygen to form solid inorganic sulfate | AMERICAN OXYCARB CORPORATION (US) | 1993-06-22 | — | — | US | claimed |
| US-5102701-A | Applying a mixture of bromochlorinated paraffin and antimony oxide with an acrylic latex binder | WEST POINT PEPERELL (US) | 1992-04-07 | — | — | US | claimed |
| US-20260007643-A1 | HIGHLY SOLUBLE FORMULATIONS OF HARMINE | RECONNECT LABS AG (CH) | 2026-01-08 | — | — | US | disclosed |
| EP-3918131-B1 | A PAPERBOARD AND A METHOD OF PRODUCING A PAPERBOARD | STORA ENSO OYJ (FI) | 2025-10-22 | — | — | EP | disclosed |
| EP-3728487-B1 | METHOD OF REMOVING POLYMERIC MATERIAL COMPRISING HETEROATOMS FROM A SURFACE USING COMPOSITIONS INCLUDING A KETO-ESTER COMPOUND | FOURTH PRINCIPLE LLC (US) | 2025-07-02 | — | — | EP | disclosed |
| EP-4561527-A2 | HIGHLY SOLUBLE FORMULATIONS OF HARMINE | Reconnect Labs AG (CH) | 2025-06-04 | — | — | EP | disclosed |
| EP-4561573-A1 | DEXMEDETOMIDINE FOR THE TREATMENT OF SLEEP DISORDERS | Universität Zürich (CH) | 2025-06-04 | — | — | EP | disclosed |
| CN-119968198-A | High solubility harmine preparation | 莱科奈科特实验室股份公司 | 2025-05-09 | — | — | CN | disclosed |
| EP-0113978-A1 | Fabric washing process | UNILEVER PLC (GB) | 1984-07-25 | — | — | EP | disclosed |
| US-4452909-A | USING ALKALI METAL SILICATES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-06-05 | — | — | US | disclosed |
| EP-0106158-A2 | Process for coating crystalline silica polymorphs | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-04-25 | — | — | EP | disclosed |
| US-4407722-A | DELAY OF REACTION BETWEEN SECONDARY BUILDER AND CALCIUM HARDNESS | LEVER BROTHERS COMPANY (US) | 1983-10-04 | — | — | US | disclosed |
| EP-0068721-A1 | Fabric washing process and detergent composition for use therein | UNILEVER N.V. (NL) | 1983-01-05 | — | — | EP | disclosed |
| US-4237147-A | CARBONATED BEVERAGE CONCENTRATE, NONTOXIC ACID | MONSANTO COMPANY (US) | 1980-12-02 | — | — | US | disclosed |
| US-4137218-A | MOLDING MATERIALS | ALLIED CHEMICAL CORPORATION (US) | 1979-01-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260007643-A1 | HIGHLY SOLUBLE FORMULATIONS OF HARMINE | SLC6A2, SLC7A1, DLST | CA4 1939/4885CA1 851/4885FAHD1 3490/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.