Bicarbonate

Bicarbonate

SCHEMBL5680462

O.O.O.O=C([O-])[O-].[Ca+2]

nearest known ligand 0.00

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Known targets — ChEMBL curated mechanism

GSK3AGSK3BIMPA1

The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bicarbonate SCHEMBL175616 1.00
Bicarbonate SCHEMBL7631660 1.00
Bicarbonate SCHEMBL3037570 1.00 CA4 (0.46)
Bicarbonate SCHEMBL28586227 1.00 CA4 (0.46)
Bicarbonate SCHEMBL17746828 1.00
Bicarbonate SCHEMBL28043173 1.00 CA4 (0.46)
Bicarbonate SCHEMBL3976963 1.00 CA4 (0.46)
Bicarbonate SCHEMBL14563714 0.94 CA4 (0.42)
Bicarbonate SCHEMBL5557766 0.94
Bicarbonate SCHEMBL10788717 0.94 CA4 (0.42)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4055085-B1 HIGH TEMPERATURE RESISTANT DUAL COMPONENT SILICONE ADHESIVE HENKEL AG & CO KGAA (DE) 2026-01-21 EP disclosed
EP-4055085-A1 HIGH TEMPERATURE RESISTANT DUAL COMPONENT SILICONE ADHESIVE Henkel AG & Co. KGaA (DE) 2022-09-14 EP disclosed
US-20220259473-A1 HIGH TEMPERATURE RESISTANT DUAL COMPONENT SILICONE ADHESIVE HENKEL AG & CO KGAA (DE) 2022-08-18 US disclosed
EP-1152738-B8 TREATMENT FOR DENTIN SENSITIVITY WITH AQUEOUS DISPERSIONS OF HYDROPHOBE-CO-HYDROPHILE COPOLYMERS BLOCK DRUG CO (US) 2006-02-01 EP disclosed
EP-1152738-B1 TREATMENT FOR DENTIN SENSITIVITY WITH AQUEOUS DISPERSIONS OF HYDROPHOBE-CO-HYDROPHILE COPOLYMERS BLOCK DRUG CO (US) 2005-11-02 EP disclosed
EP-1152738-A1 TREATMENT FOR DENTIN SENSITIVITY WITH AQUEOUS DISPERSIONS OF HYDROPHOBE-CO-HYDROPHILE COPOLYMERS Block Drug, Inc. (US) 2001-11-14 EP disclosed
US-6241972-B1 DENTIFRICE INCLUDING A DESENSITIZING AGENT COMPRISING AN ADDITION COPOLYMER OF A LONG-CHAIN A-OLEFIN HYDROPHOBIC MONOMER AND A HYDROPHILIC PARTIALLY/FULLY HYDROLYZED ACRYLIC MONOMER OR ITS SALT BLOCK DRUG COMPANY, INC. 2001-06-05 US disclosed
WO-2000048561-A1 TREATMENT FOR DENTIN SENSITIVITY WITH AQUEOUS DISPERSIONS OF HYDROPHOBE-CO-HYDROPHILE COPOLYMERS BLOCK DRUG COMPANY, INC. (US) 2000-08-24 WO disclosed
EP-0050982-B1 SMOKE SUPPRESSANT POLYMER COMPOSITIONS BICC Public Limited Company (GB) 1985-01-02 EP disclosed
EP-0050982-A2 Smoke suppressant polymer compositions BICC Public Limited Company (GB) 1982-05-05 EP disclosed