Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 10/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.35 |
| ▸ | CTSK | P43235 | 3/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | PREP | P48147 | 1/20 | 0.31 |
| ▸ | ENO1 | P06733 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28282832 | 0.92 | CTSK (0.36) | MEN1ALDH1A1MAPTKMT2ADPP4 | |
| SCHEMBL28259769 | 0.92 | CTSK (0.36) | MEN1ALDH1A1MAPTKMT2ADPP4 | |
| SCHEMBL27670177 | 0.85 | MEN1 (0.34) | MEN1ALDH1A1MAPTKMT2AHPGD | |
| SCHEMBL2377044 | 0.85 | DPP4 (0.32) | MEN1ALDH1A1MAPTKMT2ADPP4 | |
| SCHEMBL2394609 | 0.85 | DPP4 (0.32) | MEN1ALDH1A1MAPTKMT2ADPP4 | |
| SCHEMBL27997009 | 0.82 | CTSK (0.35) | MEN1ALDH1A1MAPTKMT2ADPP4 | |
| SCHEMBL28197524 | 0.78 | MEN1 (0.40) | MEN1ALDH1A1MAPTKMT2ADPP4 | |
| SCHEMBL18166955 | 0.78 | CHRM2 (0.33) | MEN1ALDH1A1MAPTKMT2AHSD11B1 | |
| SCHEMBL27698740 | 0.78 | ALDH1A1 (0.40) | MEN1ALDH1A1MAPTKMT2AHPGD | |
| SCHEMBL2379450 | 0.76 | CTSK (0.31) | CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105163738-A | MK2 inhibitors and uses thereof | CELGENE AVILOMICS RES INC | 2015-12-16 | — | — | CN | disclosed |