Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 7/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27821304 | 0.87 | CACNA1F (0.45) | ADRB3ADRA1AADRA2CKDM4E | |
| SCHEMBL3133618 | 0.87 | AURKA (0.45) | ADRB3ADRA1AADRA2CADRA1BKDM4E | |
| SCHEMBL3125091 | 0.84 | ADRB3 (0.39) | ADRB3ADRA1AADRA2CADRA1BADRB1 | |
| SCHEMBL15946008 | 0.78 | AURKA (0.47) | ADRB3ADRA1AADRA2CKDM4E | |
| SCHEMBL3132483 | 0.76 | HTR6 (0.58) | ADRB3HTR6 | |
| SCHEMBL3133713 | 0.76 | ACLY (0.41) | ADRB3 | |
| SCHEMBL13323561 | 0.74 | ADRB3 (0.43) | ADRB3ADRA1AADRA2CADRB1KDM4E | |
| SCHEMBL2150585 | 0.74 | ADRB3 (0.43) | ADRB3ADRA1AADRA2CKDM4E | |
| SCHEMBL3130816 | 0.74 | CA1 (0.40) | ADRB3ADRA1AADRA2CADRA1BKDM4E | |
| SCHEMBL2151160 | 0.72 | ADRB3 (0.40) | ADRB3ADRA1AADRB1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102197023-B | Compounds for the treatment of ophthalmic diseases and disorders | ACUCELA INC. (US) | 2015-12-16 | — | — | CN | disclosed |