Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 17/20 | 0.61 |
| ▸ | CA2 | P00918 | 17/20 | 0.61 |
| ▸ | CA9 | Q16790 | 13/20 | 0.61 |
| ▸ | CA5A | P35218 | 3/20 | 0.54 |
| ▸ | CA12 | O43570 | 4/20 | 0.45 |
| ▸ | CA6 | P23280 | 3/20 | 0.44 |
| ▸ | CA4 | P22748 | 2/20 | 0.44 |
| ▸ | CA7 | P43166 | 2/20 | 0.44 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | LDHA | P00338 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31598814 | 0.86 | CA1 (0.57) | CA1CA2CA9CA5ACA12 | |
| SCHEMBL386092 | 0.81 | CA1 (0.61) | CA1CA2CA9CA5ACA12 | |
| SCHEMBL6167928 | 0.79 | CA9 (0.57) | CA1CA2CA9CA5ACA12 | |
| SCHEMBL28043026 | 0.78 | CA1 (0.41) | CA1CA2CA9CA5ACA12 | |
| SCHEMBL353392 | 0.76 | CA1 (0.63) | CA1CA2CA9CA5ACA12 | |
| SCHEMBL353738 | 0.76 | CA1 (0.63) | CA1CA2CA9CA5ACA12 | |
| SCHEMBL31191409 | 0.76 | CA1 (0.63) | CA1CA2CA9CA5ACA12 | |
| SCHEMBL10788497 | 0.76 | CYP19A1 (0.59) | CA1CA2CA9CA12CA6 | |
| SCHEMBL27805191 | 0.76 | CA1 (1.00) | CA1CA2CA9CA5ACA12 | |
| SCHEMBL28871307 | 0.75 | CA1 (0.57) | CA1CA2CA9CA5ACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102197023-B | Compounds for the treatment of ophthalmic diseases and disorders | ACUCELA INC. (US) | 2015-12-16 | — | — | CN | disclosed |