Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 16/20 | 0.57 |
| ▸ | CA2 | P00918 | 16/20 | 0.57 |
| ▸ | CA9 | Q16790 | 10/20 | 0.57 |
| ▸ | CA5A | P35218 | 2/20 | 0.55 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.40 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.40 |
| ▸ | CA6 | P23280 | 2/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7445383 | 0.78 | TSHR (0.48) | CA1CA2CA9CA12CA6 | |
| SCHEMBL386092 | 0.78 | CA1 (0.61) | CA1CA2CA9CA5ACA12 | |
| SCHEMBL29575320 | 0.78 | TSHR (0.48) | CA1CA2CA9CA12CA6 | |
| SCHEMBL2511276 | 0.76 | CA1 (0.65) | CA1CA2CA9CA5ACA12 | |
| SCHEMBL31598835 | 0.76 | CA1 (0.65) | CA1CA2CA9CA5ACA12 | |
| SCHEMBL31598814 | 0.76 | CA1 (0.57) | CA1CA2CA9CA5ACA12 | |
| SCHEMBL28043229 | 0.75 | CA1 (0.61) | CA1CA2CA9CA5ACA12 | |
| SCHEMBL7437135 | 0.73 | MTNR1A (0.41) | MTNR1AMTNR1B | |
| SCHEMBL27805191 | 0.73 | CA1 (1.00) | CA1CA2CA9CA5ACA12 | |
| SCHEMBL6167928 | 0.72 | CA9 (0.57) | CA1CA2CA9CA5ACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106831648-B | The synthetic method of diazoxiide | 北京同济达药业有限公司 | 2019-03-12 | — | — | CN | disclosed |