SCHEMBL353738

SCHEMBL353738

NS(=O)(=O)c1ccccc1C(=O)O

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 9/20 0.63
CA2 P00918 9/20 0.63
CA9 Q16790 9/20 0.63
CA5A P35218 3/20 0.61
MMP1 P03956 1/20 0.60
MMP2 P08253 1/20 0.60
MMP9 P14780 1/20 0.60
MMP8 P22894 1/20 0.60
MMP13 P45452 1/20 0.60
F2 P00734 3/20 0.59
PRSS1 P07477 3/20 0.59
PRSS2 P07478 3/20 0.59
PRSS3 P35030 3/20 0.59
SMN1; SMN2 Q16637 2/20 0.56
TSHR P16473 1/20 0.56
CYP2C9 P11712 2/20 0.56
MCL1 Q07820 1/20 0.56
HSD17B10 Q99714 1/20 0.56
ALDH1A1 P00352 2/20 0.54
ALOX15 P16050 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31191409 1.00 CA1 (0.63) CA1CA2CA9CA5AMMP1
SCHEMBL28109387 0.98 CA1 (0.61) CA1CA2CA9CA5AMMP1
Hydrochloric Acid SCHEMBL3878957 0.98 CA1 (0.61) CA1CA2CA9CA5AMMP1
SCHEMBL15559032 0.84 CA1 (0.51) CA1CA2CA9CA5AMMP1
SCHEMBL353392 0.83 CA1 (0.63) CA1CA2CA9CA5AF2
SCHEMBL989207 0.82 CA1 (0.64) CA1CA2CA9MMP1MMP2
SCHEMBL30444901 0.82 CA1 (0.64) CA1CA2CA9MMP1MMP2
SCHEMBL11348903 0.82 CA1 (0.64) CA1CA2CA9MMP1MMP2
SCHEMBL10854249 0.82 CA2 (0.58) CA1CA2CA9CA5ACYP2C9
SCHEMBL3951462 0.82 G6PD (0.60) CA1CA2CA9CA5AMMP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 512 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119303086-A Pharmaceutical composition for treating autism 斯塔利克拉股份有限公司 2025-01-14 CN claimed
CN-117919275-A Dendrimer-tannic acid/iron composite nano platform loaded with copper peroxide and preparation and application thereof 东华大学 2024-04-26 CN claimed
CN-115745851-B Preparation method of o-carboxylbenzenesulfonamide 武汉强丰新特科技有限公司 2023-12-26 CN claimed
CN-111517996-B Preparation method and preparation intermediate of benzoyl sulfamoyl benzamide 河北兰升生物科技有限公司 2023-08-15 CN claimed
EP-3498297-B1 PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF AUTISM STALICLA S A (CH) 2023-06-21 EP claimed
CN-115745851-A Preparation method of o-carboxybenzene sulfonamide 武汉强丰新特科技有限公司 2023-03-07 CN claimed
US-11439627-B2 Pharmaceutical composition for the treatment of autism Stalicla S.A. (CH) 2022-09-13 US claimed
US-20210154177-A1 PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF AUTISM Stalicla S.A. (CH) 2021-05-27 US claimed
US-20210145803-A1 PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF AUTISM Stalicla S.A. (CH) 2021-05-20 US claimed
CN-110499091-B Nano-silver-chitosan modified polyphenyl sulfonamide antibacterial coating and preparation method thereof 安徽省优亲科技发展有限公司 2021-04-27 CN claimed
US-4650871-A DIURETIC, URICOSURIC KYORIN PHARMACEUTICAL CO., LTD. (JP) 1987-03-17 US claimed
CN-85108940-A The preparation method of sulfamoylbenzoic acid derivatives 1986-10-22 CN claimed
EP-0186796-A1 Sulfamoylbenzoic acid derivatives, process for their preparation KYORIN PHARMACEUTICAL CO., LTD. (JP) 1986-07-09 EP claimed
US-4585531-A SULFAMOYLBENZOIC ACID INSTITUTE PO PHISIKOCHIMIA (BG) 1986-04-29 US claimed
EP-0033042-B1 OPHTHALMIC INSERTS FOR LOWERING INTRAOCULAR PRESSURE COMPRISING CARBONIC ANHYDRASE INHIBITORS MERCK & CO. INC. (US) 1984-08-22 EP claimed
EP-0068407-A1 Aminosulfonylbenzoic acid derivatives HODOGAYA CHEMICAL CO., LTD. (JP) 1983-01-05 EP claimed
EP-0068239-A2 Sulfamoylbenzoic acid derivatives and pharmaceutical compositions comprising same MITSUI TOATSU CHEMICALS, Inc. (JP) 1983-01-05 EP claimed
US-4144140-A Method for the preparation of additives in organo-aluminum electrolyte media SIEMENS AKTIENGESELLSCHAFT (DE) 1979-03-13 US claimed
US-4071526-A Method for the preparation of additives in organo-aluminum electrolyte media SIEMENS AKTIENGESELLSCHAFT (DT) 1978-01-31 US claimed
US-4032413-A ELECTROPLATING BATH AND METHOD FOR THE ELECTRODEPOSITION OF BRIGHT ALUMINUM COATINGS SIEMENS AKTIENGESELLSCHAFT (DT) 1977-06-28 US claimed