Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 6/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25823727 | 0.85 | PNMT (0.41) | LMNAEPHX1EPHX2BCHEPTPN1 | |
| SCHEMBL2150950 | 0.84 | LMNA (0.37) | LMNAEPHX1EPHX2BCHEPTPN1 | |
| SCHEMBL15461614 | 0.84 | LMNA (0.40) | LMNAEPHX1EPHX2BCHEPTPN1 | |
| SCHEMBL2151052 | 0.83 | LMNA (0.39) | LMNAEPHX1EPHX2BCHEPTPN1 | |
| SCHEMBL2150918 | 0.83 | LMNA (0.39) | LMNAEPHX1EPHX2BCHEPTPN1 | |
| SCHEMBL25818182 | 0.83 | LMNA (0.39) | LMNAEPHX1EPHX2BCHEPTPN1 | |
| SCHEMBL15576263 | 0.83 | LMNA (0.41) | LMNAEPHX1EPHX2BCHEPTPN1 | |
| SCHEMBL15461617 | 0.83 | LMNA (0.41) | LMNAEPHX1EPHX2BCHEPTPN1 | |
| SCHEMBL2150796 | 0.83 | KMT2A (0.38) | LMNAEPHX1EPHX2BCHEPTPN1 | |
| SCHEMBL13323793 | 0.82 | TSHR (0.39) | LMNAEPHX1EPHX2BCHEPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102197023-B | Compounds for the treatment of ophthalmic diseases and disorders | ACUCELA INC. (US) | 2015-12-16 | — | — | CN | disclosed |