SCHEMBL538560

SCHEMBL538560

CCOC(=O)c1ccccc1Oc1ccccc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.68
TSHR P16473 7/20 0.65
ALDH1A1 P00352 5/20 0.62
MEN1 O00255 2/20 0.59
KMT2A Q03164 2/20 0.59
MAPK1 P28482 2/20 0.59
CTNNB1 P35222 1/20 0.57
KDM4E B2RXH2 1/20 0.57
MAPT P10636 3/20 0.56
NPSR1 Q6W5P4 2/20 0.56
RECQL P46063 1/20 0.56
HSD17B10 Q99714 2/20 0.56
L3MBTL1 Q9Y468 3/20 0.55
LMNA P02545 1/20 0.54
MAPK10 P53779 1/20 0.52
SCN1A P35498 1/20 0.52
SCN2A Q99250 1/20 0.52
SCN3A Q9NY46 1/20 0.52
POLB P06746 2/20 0.52
CYP1A2 P05177 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11424711 0.91 TSHR (0.57) SMN1; SMN2TSHRALDH1A1MEN1KMT2A
SCHEMBL4397330 0.90 TSHR (0.61) SMN1; SMN2TSHRALDH1A1MEN1KMT2A
SCHEMBL28974979 0.90 TSHR (0.74) SMN1; SMN2TSHRALDH1A1MEN1KMT2A
SCHEMBL27831715 0.89 TSHR (0.59) SMN1; SMN2TSHRALDH1A1MEN1KMT2A
SCHEMBL1656093 0.89 TSHR (0.59) SMN1; SMN2TSHRALDH1A1MEN1KMT2A
SCHEMBL28263705 0.89 ALDH1A1 (0.69) SMN1; SMN2TSHRALDH1A1MEN1KMT2A
SCHEMBL18979007 0.88 SMN1; SMN2 (0.55) SMN1; SMN2TSHRALDH1A1MEN1KMT2A
Diethyl Phthalate SCHEMBL11342742 0.88 TSHR (0.78) SMN1; SMN2TSHRALDH1A1KMT2AMAPK1
SCHEMBL28160008 0.88 ALDH1A1 (0.58) SMN1; SMN2TSHRALDH1A1MEN1KMT2A
SCHEMBL27254978 0.88 TSHR (0.57) SMN1; SMN2TSHRALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 635 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4581114-A1 IMPROVEMENTS IN OR RELATING TO ORGANIC COMPOUNDS Novozymes A/S (DK) 2025-07-09 EP claimed
US-20250163343-A1 FRAGRANCE COMPOSITIONS FOR SLEEP IMPROVEMENT INTERNATIONAL FLAVORES & FRAGRANCES INC. 2025-05-22 US claimed
EP-4486857-A1 FRAGRANCE COMPOSITIONS FOR SLEEP IMPROVEMENT International Flavors & Fragrances Inc. (US) 2025-01-08 EP claimed
US-12037461-B2 Encapped curable polyorganosiloxanes HENKEL AG & CO. KGAA (DE) 2024-07-16 US claimed
WO-2024046952-A1 IMPROVEMENTS IN OR RELATING TO ORGANIC COMPOUNDS NOVOZYMES A/S (DK) 2024-03-07 WO claimed
WO-2023168069-A1 FRAGRANCE COMPOSITIONS FOR SLEEP IMPROVEMENT INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 2023-09-07 WO claimed
EP-3660116-B1 ENDCAPPED CURABLE POLYORGANOSILOXANES HENKEL AG & CO KGAA (DE) 2023-07-26 EP claimed
CN-109096420-B Catalyst for olefin polymerization and olefin polymerization method 中国石油化工股份有限公司 2021-05-11 CN claimed
US-20200048578-A1 ORGANIC COMPOUNDS GIVAUDAN S.A. (CH) 2020-02-13 US claimed
CN-109096418-A A kind of catalyst and olefine polymerizing process for olefinic polymerization 中国石油化工股份有限公司 2018-12-28 CN claimed
WO-2008113495-A2 PERFUME COMPOSITIONS GIVAUDAN NEDERLAND SERVICES B.V. (NL) 2008-09-25 WO claimed
EP-1928406-A2 PHARMACEUTICAL COMPOSITIONS WITH MELTING POINT DEPRESSANT AGENTS AND METHOD OF MAKING SAME Antares Pharma IPL AG (CH) 2008-06-11 EP claimed
US-20070166341-A1 Solid volatile composition and method and system for making the same INTERNATIONAL ARTS & SCIENCE GROUP, INC. 2007-07-19 US claimed
WO-2007022924-A2 PHARMACEUTICAL COMPOSITIONS WITH MELTING POINT DEPRESSANT AGENTS AND METHOD OF MAKING SAME ANTARES PHARMA IPL AG (CH) 2007-03-01 WO claimed
US-20070048360-A1 Pharmaceutical compositions with melting point depressant agents and method of making same ANTARES PHARMA IPL AG (CH) 2007-03-01 US claimed
US-6555098-B1 Fragrance crystallites in the form of polymer surface-coated particles CHURCH & DWIGHT CO., INC. 2003-04-29 US claimed
WO-1998056337-A1 MALODOR REDUCING COMPOSITION CONTAINING AMBER AND MUSK MATERIALS THE PROCTER & GAMBLE COMPANY (US) 1998-12-17 WO claimed
WO-1997030686-A1 COSMETIC DEODORANT PRODUCTS CONTAINING ENCAPSULATED BICARBONATE AND FRAGRANCE INGREDIENTS CHURCH & DWIGHT COMPANY, INC. (US) 1997-08-28 WO claimed
WO-1997011677-A1 COSMETIC DEODORANT PRODUCTS CONTAINING A POLYMER/FRAGRANCE-ENCAPSULATED BICARBONATE INGREDIENT CHURCH & DWIGHT COMPANY, INC. (US) 1997-04-03 WO claimed
US-5614179-A Cosmetic deodorant products containing a polymer/fragrance-encapsulated bicarbonate ingredient CHURCH & DWIGHT CO., INC. (US) 1997-03-25 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070048360-A1 Pharmaceutical compositions with melting point depressant agents and method of making same TRPA1, TRPV1, OR51E2 SMN1; SMN2 1068/4885TSHR 3579/4885ALDH1A1 277/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.