SCHEMBL28043537

SCHEMBL28043537

Cc1cccc(-c2cc(-c3ccccc3)cc(-c3cccc(C)c3)c2)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.53
RAB9A P51151 2/20 0.53
NPC1 O15118 1/20 0.53
HPGD P15428 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
DHODH Q02127 1/20 0.53
ACHE P22303 2/20 0.52
LMNA P02545 1/20 0.48
ALOX12 P18054 1/20 0.48
AKR1C2 P52895 1/20 0.47
AKR1C1 Q04828 1/20 0.47
ENPP3 O14638 2/20 0.47
NPSR1 Q6W5P4 1/20 0.46
MAOA P21397 1/20 0.46
POLB P06746 1/20 0.46
MAPT P10636 1/20 0.46
CTDSP1 Q9GZU7 1/20 0.46
PTPN5 P54829 1/20 0.46
ALDH1A1 P00352 1/20 0.45
KMO O15229 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19503240 0.97 TSHR (0.55) TSHRRAB9ANPC1HPGDSMN1; SMN2
SCHEMBL29699277 0.95 ACHE (0.58) TSHRRAB9ANPC1HPGDSMN1; SMN2
SCHEMBL200730 0.95 ACHE (0.58) TSHRRAB9ANPC1HPGDSMN1; SMN2
Benzene SCHEMBL27980187 0.95 ACHE (0.58) TSHRRAB9ANPC1HPGDSMN1; SMN2
SCHEMBL9083578 0.93 ACHE (0.57) TSHRRAB9ANPC1HPGDSMN1; SMN2
SCHEMBL23518713 0.92 MAOA (0.48) TSHRRAB9ANPC1HPGDSMN1; SMN2
SCHEMBL30493472 0.92 ACHE (0.55) TSHRRAB9ANPC1HPGDSMN1; SMN2
SCHEMBL20689786 0.92 TSHR (0.55) TSHRRAB9ANPC1HPGDSMN1; SMN2
SCHEMBL28660662 0.92 TSHR (0.55) TSHRRAB9ANPC1HPGDSMN1; SMN2
SCHEMBL29057032 0.92 ACHE (0.55) TSHRRAB9ANPC1HPGDSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105037072-A Synthetic method for 1,3,5-triarylbenzene compound UNIV HUAQIAO 2015-11-11 CN disclosed