Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 2/20 | 0.41 |
| ▸ | MPO | P05164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TNF | P01375 | 1/20 | 0.38 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.38 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.38 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.38 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29758354 | 0.82 | BACE1 (0.50) | ALDH1A1BACE1L3MBTL1APP | |
| SCHEMBL1402167 | 0.82 | BACE1 (0.50) | ALDH1A1BACE1L3MBTL1APP | |
| SCHEMBL7796022 | 0.81 | ESR1 (0.46) | ALDH1A1SLC6A2BACE1L3MBTL1APP | |
| SCHEMBL9395340 | 0.81 | KCNH3 (0.47) | BACE1MPOL3MBTL1APP | |
| SCHEMBL17674597 | 0.80 | GAA (0.41) | HSP90AB1KMT2ABACE1L3MBTL1MAPT | |
| SCHEMBL3934154 | 0.80 | SMN1; SMN2 (0.43) | HSP90AB1MEN1KMT2ABACE1MPO | |
| SCHEMBL28043533 | 0.79 | CYP17A1 (0.47) | BACE1L3MBTL1APP | |
| SCHEMBL25802195 | 0.79 | HSP90AB1 (0.51) | HSP90AB1ALDH1A1SLC6A2SLC6A3KMT2A | |
| SCHEMBL29844302 | 0.79 | HSP90AB1 (0.51) | HSP90AB1ALDH1A1SLC6A2SLC6A3KMT2A | |
| SCHEMBL23578153 | 0.78 | HSP90AB1 (0.46) | HSP90AB1SLC6A2SLC6A3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116472047-B | Arylamine derivative, preparation method and medical application thereof | 中国医药研究开发中心有限公司 | 2025-06-17 | — | — | CN | disclosed |
| CN-116472047-A | Arylamine derivative, preparation method and medical application thereof | 中国医药研究开发中心有限公司 | 2023-07-21 | — | — | CN | disclosed |
| WO-2023078241-A1 | AROMATIC AMINE DERIVATIVES AND PREPARATION METHOD AND MEDICAL USE THEREOF | 中国医药研究开发中心有限公司 | 2023-05-11 | — | — | WO | disclosed |
| CN-105324380-A | Pyrrolo[2,3-b]pyridine cdk9 kinase inhibitors | ABBVIE INC | 2016-02-10 | — | — | CN | disclosed |
| CN-105246890-A | Pyrrolo[2, 3-b]pyridine cdk9 kinase inhibitors | ABBVIE INC | 2016-01-13 | — | — | CN | disclosed |