SCHEMBL28043646

SCHEMBL28043646

C=C(C)C(=O)OC(CCCC)COc1ccc2cc(C(=O)O)ccc2c1

nearest known ligand 0.46

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.46
APEX1 P27695 1/20 0.46
HTT P42858 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
PLA2G4B P0C869 2/20 0.45
THRA P10827 1/20 0.43
TP53 P04637 1/20 0.42
TSHR P16473 1/20 0.42
KDM4E B2RXH2 1/20 0.42
PLA2G4A P47712 1/20 0.41
RARB P10826 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28256299 0.90 POLB (0.53) POLBAPEX1HTTTDP1PLA2G4B
SCHEMBL28043853 0.84 PLA2G4A (0.38) TDP1THRAPLA2G4A
SCHEMBL29118724 0.82 ELANE (0.52) POLBAPEX1HTTTDP1PLA2G4B
SCHEMBL28466290 0.82 RARB (0.46) RARB
SCHEMBL28852196 0.82 PLA2G4B (0.44) PLA2G4BTHRATP53TSHRKDM4E
SCHEMBL28255141 0.81 ALOX5 (0.43) POLBAPEX1HTTTDP1TSHR
SCHEMBL30337406 0.81 HTT (0.64) POLBAPEX1HTTTDP1PLA2G4B
SCHEMBL15302401 0.80 AKR1C3 (0.43)
SCHEMBL15463535 0.79 TDP1 (0.43) POLBHTTTDP1TP53KDM4E
SCHEMBL8086481 0.79 PLA2G4B (0.52) PLA2G4BTHRATP53TSHRKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103732638-B Copolymer and liquid crystal alignment layer comprising cured product of the copolymer DIC CORP. (JP) 2016-01-20 CN disclosed
CN-105037617-A Copolymer, liquid crystal alignment layer, liquid crystal display element and optically anisotropic body DAINIPPON INK & CHEMICALS 2015-11-11 CN disclosed