Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | XBP1 | P17861 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | CASP1 | P29466 | 2/20 | 0.45 |
| ▸ | CASP7 | P55210 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28043741 | 0.86 | KMT2A (0.50) | CYP2D6CYP2C9KMT2AGAASMN1; SMN2 | |
| SCHEMBL28043739 | 0.85 | ALDH1A1 (0.54) | HPGDKMT2AGAASMN1; SMN2MAPK1 | |
| SCHEMBL28043745 | 0.82 | KMT2A (0.46) | CYP1A2CYP2D6CYP2C9HPGDKMT2A | |
| SCHEMBL28043490 | 0.82 | KMT2A (0.46) | CYP1A2CYP2D6CYP2C9HPGDKMT2A | |
| SCHEMBL28043488 | 0.81 | MAPT (0.46) | CYP1A2KMT2AGAASMN1; SMN2MAPK1 | |
| SCHEMBL18990995 | 0.78 | MAPT (0.49) | CYP1A2CYP2C9KMT2AGAASMN1; SMN2 | |
| SCHEMBL18990217 | 0.75 | GAA (0.49) | KMT2AGAASMN1; SMN2MAPK1MAPT | |
| SCHEMBL28043747 | 0.74 | BRDT (0.53) | KMT2AGAASMN1; SMN2MAPK1MAPT | |
| SCHEMBL28043736 | 0.72 | DHFR (0.41) | KMT2AGAASMN1; SMN2MAPK1MAPT | |
| SCHEMBL15923525 | 0.72 | GAA (0.47) | KMT2AGAASMN1; SMN2MAPK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102807568-B | Thiadiazoles derivative class DPP-IV inhibitor | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD. (CN) | 2015-11-25 | — | — | CN | disclosed |