Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28095288 | 0.88 | MAPT (0.43) | MAPTDNM1ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL28292762 | 0.78 | TAAR1 (0.52) | KDM4EL3MBTL1KMT2A | |
| SCHEMBL11604193 | 0.78 | POLB (0.42) | ADRB2MAPTKDM4EALDH1A1HTT | |
| SCHEMBL1936242 | 0.76 | BCAT2 (0.43) | KDM4EL3MBTL1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL28053814 | 0.74 | CYP2D6 (0.42) | KDM4EL3MBTL1ALDH1A1LMNA | |
| SCHEMBL2308839 | 0.74 | MAPT (0.52) | ADRB2MAPTKDM4EL3MBTL1DNM1 | |
| SCHEMBL10627463 | 0.74 | CYP2D6 (0.42) | KDM4EL3MBTL1ALDH1A1LMNAKMT2A | |
| SCHEMBL10402855 | 0.74 | MAPT (0.49) | ADRB2MAPTKDM4EL3MBTL1DNM1 | |
| SCHEMBL2001329 | 0.71 | CYP2D6 (0.39) | KDM4EL3MBTL1ALDH1A1LMNAKMT2A | |
| SCHEMBL10584869 | 0.71 | CYP2D6 (0.39) | KDM4EL3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105143281-B | Tridentate nitrogen-based ligands for olefin polymerization catalysts | 尤尼威蒂恩技术有限责任公司 | 2018-06-01 | — | — | CN | disclosed |
| CN-105143281-A | Tridentate nitrogen-based ligands for olefin polymerization catalysts | UNIVATION TECH LLC | 2015-12-09 | — | — | CN | disclosed |