Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 2/20 | 0.44 |
| ▸ | HRH1 | P35367 | 2/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 14/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 14/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 12/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 7/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 7/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28048068 | 0.79 | HIF1A (0.61) | TAAR1HTR2ASLC6A3KDM4EKMT2A | |
| SCHEMBL28044007 | 0.78 | ADRB2 (0.41) | KDM4EL3MBTL1KMT2A | |
| SCHEMBL13192549 | 0.78 | HTR2A (0.62) | TAAR1HTR2AHRH1SLC6A2SLC6A4 | |
| SCHEMBL1936242 | 0.77 | BCAT2 (0.43) | TAAR1CYP2D6KDM4EL3MBTL1KMT2A | |
| SCHEMBL218804 | 0.77 | LMNA (0.46) | TAAR1HTR2AHRH1CYP2D6KDM4E | |
| SCHEMBL13452609 | 0.77 | LMNA (0.46) | TAAR1HTR2AHRH1CYP2D6KDM4E | |
| SCHEMBL3276260 | 0.77 | LMNA (0.46) | TAAR1HTR2AHRH1CYP2D6KDM4E | |
| SCHEMBL31038339 | 0.77 | CHRM2 (0.50) | SLC6A2SLC6A4KDM4EL3MBTL1AOC3 | |
| SCHEMBL10627463 | 0.76 | CYP2D6 (0.42) | TAAR1HTR2AHRH1CYP2D6KDM4E | |
| SCHEMBL28053814 | 0.76 | CYP2D6 (0.42) | TAAR1HTR2AHRH1CYP2D6KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109721521-A | A kind of preparation method of optical activity clausenamide ketone and its derivative | 广东药科大学 | 2019-05-07 | — | — | CN | claimed |
| CN-109796352-B | Ortho-alkylated arylamine and preparation method thereof | 广东工业大学 | 2022-02-15 | — | — | CN | disclosed |
| CN-109721521-A | A kind of preparation method of optical activity clausenamide ketone and its derivative | 广东药科大学 | 2019-05-07 | — | — | CN | disclosed |
| CN-109627199-A | A kind of optical activity clausenamide ketone derivatives and its application | 广东药科大学 | 2019-04-16 | — | — | CN | disclosed |