Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TKT | P29401 | 6/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL30223517 | 0.78 | TDP1 (0.58) | TKTLMNA | |
| SCHEMBL27970697 | 0.75 | TKT (0.49) | TKTLMNAHSP90AA1 | |
| SCHEMBL27987171 | 0.72 | TKT (0.44) | TKTLMNAHSP90AA1 | |
| SCHEMBL4358570 | 0.69 | LMNA (0.61) | TKTLMNAHSP90AA1NFKB1BLM | |
| Beclotiamine Ion SCHEMBL24787578 | 0.69 | HSP90AA1 (0.78) | TKTLMNAHSP90AA1 | |
| Beclotiamine Ion SCHEMBL29733080 | 0.69 | HSP90AA1 (0.78) | TKTLMNAHSP90AA1 | |
| SCHEMBL10590003 | 0.69 | TKT (0.49) | TKTLMNAHSP90AA1 | |
| Beclotiamine Ion SCHEMBL2110727 | 0.68 | HSP90AA1 (0.76) | TKTLMNAHSP90AA1 | |
| Beclotiamine Ion SCHEMBL29733109 | 0.68 | HSP90AA1 (0.76) | TKTLMNAHSP90AA1 | |
| Hydrochloric Acid SCHEMBL7810783 | 0.68 | LMNA (0.59) | TKTLMNANFKB1BLMPMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103664924-B | The preparation method of 3-[(4-amino-2-methyl-5-pyrimidyl) methyl]-5-(2-chloroethyl)-4-methylthiazol | JIANGXI TIANXIN PHARMACEUTICAL CO., LTD. (CN) | 2015-12-02 | — | — | CN | disclosed |
| CN-103664924-B | The preparation method of 3-[(4-amino-2-methyl-5-pyrimidyl) methyl]-5-(2-chloroethyl)-4-methylthiazol | JIANGXI TIANXIN PHARMACEUTICAL CO., LTD. (CN) | 2015-12-02 | — | — | CN | disclosed |