Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TKT | P29401 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10686150 | 0.71 | LMNA (0.59) | TKTLMNAKDM4EALDH1A1 | |
| SCHEMBL23748348 | 0.70 | LMNA (0.63) | TKTLMNAKDM4EALDH1A1HSP90AA1 | |
| SCHEMBL12346332 | 0.70 | LMNA (0.63) | TKTLMNAKDM4EALDH1A1 | |
| SCHEMBL29895545 | 0.70 | LMNA (0.63) | TKTLMNAKDM4EALDH1A1HSP90AA1 | |
| SCHEMBL478879 | 0.70 | LMNA (0.63) | TKTLMNAKDM4EALDH1A1HSP90AA1 | |
| SCHEMBL15369436 | 0.69 | LMNA (0.58) | TKTLMNAKDM4EALDH1A1 | |
| SCHEMBL16470251 | 0.69 | BACE1 (0.39) | TKTALDH1A1 | |
| SCHEMBL28044147 | 0.69 | TKT (0.49) | TKTLMNAHSP90AA1 | |
| SCHEMBL27970697 | 0.69 | TKT (0.49) | TKTLMNAKDM4EALDH1A1HSP90AA1 | |
| SCHEMBL3787961 | 0.69 | FDPS (0.47) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0329184-A2 | Antimers and antimeric conjugation | NEORX CORPORATION (US) | 1989-08-23 | — | — | EP | disclosed |