Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 8/20 | 0.54 |
| ▸ | PPARG | P37231 | 5/20 | 0.54 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.46 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28044220 | 0.82 | CYP4F2 (0.39) | PPARAPPARGTRPV1 | |
| SCHEMBL28337010 | 0.81 | PPARA (0.62) | PPARAPPARG | |
| SCHEMBL3404983 | 0.80 | PPARA (0.61) | PPARAPPARG | |
| SCHEMBL29328712 | 0.79 | PPARA (0.64) | PPARAPPARG | |
| SCHEMBL646706 | 0.79 | PPARA (0.64) | PPARAPPARG | |
| SCHEMBL27678746 | 0.79 | PLAU (0.46) | — | |
| SCHEMBL29328704 | 0.78 | PPARA (0.63) | PPARAPPARG | |
| SCHEMBL29328706 | 0.78 | PPARA (0.63) | PPARAPPARG | |
| SCHEMBL29328702 | 0.78 | PPARA (0.63) | PPARAPPARG | |
| SCHEMBL28392302 | 0.78 | PPARA (0.63) | PPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105143170-A | Substituted aromatic compounds for the treatment of pulmonary fibrosis, liver fibrosis, skin fibrosis and cardiac fibrosis | PROMETIC BIOSCIENCES INC | 2015-12-09 | — | — | CN | disclosed |