Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 18/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | GNA15 | P30679 | 1/20 | 0.36 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.36 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.36 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.36 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL205960 | 0.82 | FFAR1 (0.57) | FFAR1GNA15SLC10A1ABCC2SLCO1B3 | |
| SCHEMBL1974835 | 0.77 | BRD4 (0.55) | BRD4FFAR1CA12CA1CA2 | |
| SCHEMBL204988 | 0.75 | FFAR1 (0.52) | BRD4FFAR1 | |
| SCHEMBL1745297 | 0.74 | BRD4 (0.58) | BRD4FFAR1CA12CA1CA2 | |
| SCHEMBL16552739 | 0.73 | CA12 (0.41) | BRD4FFAR1CA12CA1CA2 | |
| SCHEMBL204829 | 0.73 | FFAR1 (0.49) | BRD4FFAR1CA12CA1CA2 | |
| SCHEMBL207347 | 0.72 | FFAR1 (0.49) | FFAR1GNA15SLC10A1ABCC2SLCO1B3 | |
| SCHEMBL661751 | 0.71 | PTGS2 (0.44) | FFAR1CA12CA1CA2CA9 | |
| SCHEMBL205804 | 0.71 | BRD4 (0.53) | BRD4FFAR1CA12CA1CA2 | |
| SCHEMBL10058614 | 0.71 | FFAR1 (0.74) | FFAR1GNA15SLC10A1ABCC2SLCO1B3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105143181-B | Ternary and ring carboxylic acid derivative, its preparation method and its application in medicine | 四川海思科制药有限公司 | 2017-12-26 | — | — | CN | disclosed |
| CN-105143181-A | Triadic fused cyclic carboxylic acids derivatives, preparation method therefor and pharmaceutical use thereof | SICHUAN HAISCO PHARMACEUTICAL CO LTD | 2015-12-09 | — | — | CN | disclosed |