Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.53 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.46 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | UNG | P13051 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1974835 | 0.86 | BRD4 (0.55) | BRD4TRIM24TRIM33CA12CA1 | |
| SCHEMBL1745297 | 0.85 | BRD4 (0.58) | BRD4TRIM24TRIM33CA12CA1 | |
| SCHEMBL203685 | 0.80 | BRD4 (0.47) | BRD4TRIM24TRIM33CA12CA1 | |
| SCHEMBL2911266 | 0.80 | ESR2 (0.59) | BRD4TRIM24TRIM33CA12CA1 | |
| SCHEMBL24028046 | 0.79 | MAOA (0.39) | BRD4TRIM24TRIM33CA12CA1 | |
| SCHEMBL205798 | 0.79 | BRD4 (0.53) | BRD4TRIM24TRIM33CA12CA1 | |
| SCHEMBL12577722 | 0.79 | BRD4 (0.49) | BRD4TRIM24TRIM33CA12CA1 | |
| SCHEMBL2022257 | 0.79 | BRD4 (0.49) | BRD4TRIM24TRIM33CA12CA1 | |
| SCHEMBL16347706 | 0.79 | BRD4 (0.46) | BRD4TRIM24TRIM33CA12CA1 | |
| SCHEMBL204011 | 0.79 | BRD4 (0.46) | BRD4TRIM24TRIM33CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105143181-B | Ternary and ring carboxylic acid derivative, its preparation method and its application in medicine | 四川海思科制药有限公司 | 2017-12-26 | — | — | CN | disclosed |
| US-20160200734-A1 | CARBOXYLIC ACID COMPOUNDS IN TREATMENT OF DIABETES MELLITUS | KANG, XINSHAN (CN) | 2016-07-14 | — | — | US | disclosed |
| US-20160200734-A1 | CARBOXYLIC ACID COMPOUNDS IN TREATMENT OF DIABETES MELLITUS | KANG, XINSHAN (CN) | 2016-07-14 | — | — | US | disclosed |
| US-20160200734-A1 | CARBOXYLIC ACID COMPOUNDS IN TREATMENT OF DIABETES MELLITUS | KANG, XINSHAN (CN) | 2016-07-14 | — | — | US | disclosed |
| EP-3036237-A1 | CARBOXYLIC ACID COMPOUNDS IN TREATMENT OF DIABETES MELLITUS | Fujian Haixi Pharmaceuticals Co. Ltd (CN) | 2016-06-29 | — | — | EP | disclosed |
| CN-105246875-A | Indane derivative, preparation method therefor, and pharmaceutical application thereof | SICHUAN HAISCO PHARMACEUTICAL CO LTD | 2016-01-13 | — | — | CN | disclosed |
| CN-105143181-A | Triadic fused cyclic carboxylic acids derivatives, preparation method therefor and pharmaceutical use thereof | SICHUAN HAISCO PHARMACEUTICAL CO LTD | 2015-12-09 | — | — | CN | disclosed |
| US-9139548-B2 | Polycyclic derivatives, preparation process and pharmaceutical use thereof | JIANGSU HENGRUI MEDICINE CO., LTD. (CN) | 2015-09-22 | — | — | US | disclosed |
| US-9139548-B2 | Polycyclic derivatives, preparation process and pharmaceutical use thereof | JIANGSU HENGRUI MEDICINE CO., LTD. (CN) | 2015-09-22 | — | — | US | disclosed |
| CN-104592211-A | Biphenyl compound and use thereof | GUANGDONG HEC PHARMACEUTICAL | 2015-05-06 | — | — | CN | disclosed |
| US-20080269220-A1 | Aminophenylpropanoic Acid Derivative | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-10-30 | — | — | US | disclosed |
| US-20080269220-A1 | Aminophenylpropanoic Acid Derivative | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-10-30 | — | — | US | disclosed |
| EP-1916234-A1 | CYCLOPROPANECARBOXYLIC ACID COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2008-04-30 | — | — | EP | disclosed |
| EP-1916234-A1 | CYCLOPROPANECARBOXYLIC ACID COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2008-04-30 | — | — | EP | disclosed |
| US-20070149608-A1 | 3-(4-Benzyloxyphenyl) propanoic acid derivatives | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-06-28 | — | — | US | disclosed |
| US-20070149608-A1 | 3-(4-Benzyloxyphenyl) propanoic acid derivatives | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-06-28 | — | — | US | disclosed |
| US-20070149608-A1 | 3-(4-Benzyloxyphenyl) propanoic acid derivatives | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-06-28 | — | — | US | disclosed |
| EP-1726580-A1 | AMINOPHENYLPROPANOIC ACID DERIVATIVE | Takeda Pharmaceutical Company Limited (JP) | 2006-11-29 | — | — | EP | disclosed |
| US-20060258722-A1 | Condensed ring compound | TAKEDA PHARMACEUTICAL COMPANY., LTD. (JP) | 2006-11-16 | — | — | US | disclosed |
| EP-1630152-A1 | CONDENSED RING COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2006-03-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160200734-A1 | CARBOXYLIC ACID COMPOUNDS IN TREATMENT OF DIABETES MELLITUS | GPR119, GLP1R, INSR | BRD4 2917/4885TRIM24 3506/4885TRIM33 3875/4885 |
| US-20070149608-A1 | 3-(4-Benzyloxyphenyl) propanoic acid derivatives | GPR119, GPR55, GLP1R | BRD4 1422/4885TRIM24 2107/4885TRIM33 2060/4885 |
| US-20080269220-A1 | Aminophenylpropanoic Acid Derivative | GPR119, GPR55, GPR65 | BRD4 2707/4885TRIM24 2547/4885TRIM33 1696/4885 |
| US-20060258722-A1 | Condensed ring compound | GPR119, GLP1R, GCGR | BRD4 277/4885TRIM24 1608/4885TRIM33 1268/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.