Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | DTYMK | P23919 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | MMP14 | P50281 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28044440 | 0.99 | HCAR3 (0.41) | HCAR3ALDH1A1DTYMKMAPTNPSR1 | |
| SCHEMBL27785428 | 0.85 | HCAR3 (0.44) | HCAR3ALDH1A1DTYMKMAPTNPSR1 | |
| SCHEMBL28044438 | 0.85 | HCAR3 (0.45) | HCAR3ALDH1A1DTYMKMAPTNPSR1 | |
| Hydrochloric Acid SCHEMBL590351 | 0.84 | HCAR3 (0.43) | HCAR3ALDH1A1DTYMKMAPTNPSR1 | |
| Hydrochloric Acid SCHEMBL28824557 | 0.84 | HCAR3 (0.44) | HCAR3ALDH1A1DTYMKMAPTNPSR1 | |
| SCHEMBL28144494 | 0.83 | MAPT (0.34) | HCAR3ALDH1A1MAPTNPSR1PTGS2 | |
| Hydrochloric Acid SCHEMBL591231 | 0.82 | MMP14 (0.42) | HCAR3ALDH1A1DTYMKMAPTNPSR1 | |
| SCHEMBL27785401 | 0.81 | HCAR3 (0.41) | HCAR3ALDH1A1DTYMKMAPTNPSR1 | |
| Hydrochloric Acid SCHEMBL590920 | 0.80 | HCAR3 (0.40) | HCAR3ALDH1A1DTYMKMAPTNPSR1 | |
| SCHEMBL1371283 | 0.79 | MAPT (0.57) | HCAR3ALDH1A1DTYMKMAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101594862-B | Substituted indazole derivatives as kinase inhibitors | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2015-11-25 | — | — | CN | disclosed |