Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 2/20 | 0.54 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.42 |
| ▸ | THRA | P10827 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL592445 | 0.99 | CHRNB2 (0.53) | CHRNB2CHRNA4KDM4EGAAALDH1A1 | |
| SCHEMBL16095626 | 0.88 | CHRNB2 (0.53) | CHRNB2CHRNA4KDM4EGAAALDH1A1 | |
| SCHEMBL1749050 | 0.85 | PLA2G4B (0.53) | ALDH1A1LMNAMAPTTDP1AKR1C3 | |
| SCHEMBL591158 | 0.84 | CHRNB2 (0.49) | CHRNB2CHRNA4KDM4EGAAALDH1A1 | |
| SCHEMBL3512088 | 0.84 | AKR1C3 (0.46) | KDM4EALDH1A1MAPTAKR1C3AKR1C2 | |
| SCHEMBL30344322 | 0.81 | CHRNB2 (0.59) | CHRNB2CHRNA4KDM4EGAAALDH1A1 | |
| SCHEMBL311014 | 0.81 | CHRNB2 (0.59) | CHRNB2CHRNA4KDM4EGAAALDH1A1 | |
| SCHEMBL213189 | 0.80 | CHRNB2 (0.62) | CHRNB2CHRNA4KDM4EGAAALDH1A1 | |
| SCHEMBL16655258 | 0.80 | CHRNB2 (0.58) | CHRNB2CHRNA4KDM4EGAAALDH1A1 | |
| SCHEMBL29740481 | 0.80 | AKR1C3 (0.46) | ALDH1A1LMNAMAPTTDP1AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101594862-B | Substituted indazole derivatives as kinase inhibitors | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2015-11-25 | — | — | CN | disclosed |