Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.44 |
| ▸ | PIK3CD | O00329 | 8/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.39 |
| ▸ | LIPE | Q05469 | 2/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | SPR | P35270 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28044502 | 0.83 | PIK3CD (0.39) | NR1H2PIK3CDUSP30LIPESPR | |
| SCHEMBL1881390 | 0.71 | ESR2 (0.47) | NR1H2CNR1 | |
| SCHEMBL20557865 | 0.71 | ELANE (0.39) | NR1H2PIK3CDCNR1 | |
| SCHEMBL16993112 | 0.70 | NR1H2 (0.60) | NR1H2GPR119 | |
| SCHEMBL16993114 | 0.70 | NR1H2 (0.60) | NR1H2GPR119 | |
| SCHEMBL28044588 | 0.69 | NR1H2 (0.44) | NR1H2USP30LIPERORCSPR | |
| SCHEMBL28044510 | 0.69 | USP30 (0.42) | NR1H2PIK3CDUSP30LIPERORC | |
| SCHEMBL5940329 | 0.68 | NR1H2 (0.54) | NR1H2USP30LIPERORCPDE4B | |
| SCHEMBL5938643 | 0.68 | NR1H2 (0.54) | NR1H2USP30LIPERORCPDE4B | |
| SCHEMBL22484217 | 0.66 | NR1H2 (0.52) | NR1H2GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105085530-A | Fused tricyclic substituted amino six-membered ring derivative and application thereof in medicine | SICHUAN HAISCO PHARMACEUTICAL CO LTD | 2015-11-25 | — | — | CN | disclosed |