Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 8/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | SPR | P35270 | 1/20 | 0.35 |
| ▸ | LIPE | Q05469 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28044586 | 0.83 | NR1H2 (0.44) | PIK3CDNR1H2GPR119USP30SPR | |
| SCHEMBL7989746 | 0.76 | SMN1; SMN2 (0.39) | SMN1; SMN2GPR119LMNAMEN1ALDH1A1 | |
| SCHEMBL7975140 | 0.74 | ESR2 (0.44) | NR1H2SMN1; SMN2GPR119LMNAMEN1 | |
| SCHEMBL22629402 | 0.72 | NR1H2 (0.51) | NR1H2SMN1; SMN2GPR119ALDH1A1 | |
| SCHEMBL7986449 | 0.70 | SMN1; SMN2 (0.40) | SMN1; SMN2LMNAMEN1ALDH1A1KMT2A | |
| SCHEMBL28044510 | 0.68 | USP30 (0.42) | PIK3CDNR1H2GPR119USP30LIPE | |
| SCHEMBL19816595 | 0.68 | NR1H2 (0.44) | NR1H2GPR119MEN1ALDH1A1KMT2A | |
| SCHEMBL31364874 | 0.68 | NR1H2 (0.44) | NR1H2GPR119MEN1ALDH1A1KMT2A | |
| SCHEMBL13744392 | 0.68 | NR1H2 (0.44) | NR1H2SMN1; SMN2GPR119MEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7989639 | 0.67 | SMN1; SMN2 (0.39) | SMN1; SMN2LMNAMEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105085530-A | Fused tricyclic substituted amino six-membered ring derivative and application thereof in medicine | SICHUAN HAISCO PHARMACEUTICAL CO LTD | 2015-11-25 | — | — | CN | disclosed |