Toluene

Toluene

SCHEMBL28044613

Cc1ccccc1.NNC(=O)N=S(=O)=O

nearest known ligand 0.41

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.41
TSHR P16473 1/20 0.41
ALOX12 P18054 1/20 0.41
ACHE P22303 1/20 0.41
NPC1 O15118 3/20 0.39
RAB9A P51151 3/20 0.39
KMT2A Q03164 3/20 0.39
MEN1 O00255 2/20 0.39
CES2 O00748 1/20 0.38
CES1 P23141 1/20 0.38
KDM4E B2RXH2 1/20 0.38
SMN1; SMN2 Q16637 3/20 0.37
MAPT P10636 1/20 0.37
HDAC4 P56524 2/20 0.37
CTSD P07339 1/20 0.36
POLB P06746 1/20 0.36
PTGS2 P35354 1/20 0.35
CNR1 P21554 1/20 0.35
CNR2 P34972 1/20 0.35
SCN2A Q99250 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
P-Xylene SCHEMBL28085495 0.90 KDM4E (0.46) LMNANPC1RAB9AKMT2AMEN1
Phenol SCHEMBL27937377 0.83 TDP1 (0.42) LMNANPC1RAB9AKMT2AMEN1
Naphthalene SCHEMBL28299668 0.82 GAA (0.39) ALOX12NPC1KMT2AMEN1CES2
Toluene SCHEMBL11475268 0.80 LMNA (0.58) LMNATSHRALOX12ACHENPC1
Toluene SCHEMBL8664108 0.79 LMNA (0.38) LMNATSHRALOX12ACHENPC1
Toluene SCHEMBL8599249 0.79 LMNA (0.46) LMNATSHRALOX12ACHENPC1
SCHEMBL6295418 0.77
Toluene SCHEMBL10321989 0.76 LMNA (0.53) LMNATSHRALOX12ACHENPC1
Toluene SCHEMBL27502728 0.76 LMNA (0.52) LMNATSHRALOX12ACHENPC1
Toluene SCHEMBL27504214 0.76 LMNA (0.52) LMNATSHRALOX12ACHENPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105086430-B Amilan polyamide resin composition and its formed body 尤尼蒂卡株式会社 2019-05-10 CN disclosed
CN-109423043-A Foaming Amilan polyamide resin composition, foaming polyamide granulate mixture and expanded moldings 尤尼吉可株式会社 2019-03-05 CN disclosed
CN-105086430-A Polyamide resin composition and formation body thereof UNITIKA LTD 2015-11-25 CN disclosed