Sugi Predict

Sugi Predict / Compounds / Toluene

Toluene

Toluene

SCHEMBL8599249

Cc1ccccc1.NC(=O)N=S(=O)=O

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 2/20 0.46
▸ TSHR P16473 2/20 0.46
▸ ALOX12 P18054 1/20 0.46
▸ ACHE P22303 1/20 0.46
▸ CES2 O00748 1/20 0.42
▸ CES1 P23141 1/20 0.42
▸ CYP2D6 P10635 1/20 0.40
▸ HIF1A Q16665 1/20 0.40
▸ PARP1 P09874 2/20 0.39
▸ USP2 O75604 2/20 0.39
▸ NPC1 O15118 3/20 0.38
▸ RAB9A P51151 3/20 0.38
▸ KMT2A Q03164 2/20 0.38
▸ MEN1 O00255 1/20 0.38
▸ L3MBTL1 Q9Y468 4/20 0.38
▸ MAPT P10636 5/20 0.38
▸ POLB P06746 1/20 0.38
▸ CYP3A4 P08684 1/20 0.38
▸ CYP2C19 P33261 1/20 0.38
▸ RECQL P46063 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Toluene SCHEMBL28749878 0.91 LMNA (0.38) LMNATSHRALOX12ACHECES2
Benzene SCHEMBL3120365 0.82 CYP3A4 (0.37) LMNATSHRACHEPARP1L3MBTL1
Toluene SCHEMBL29226068 0.81 NQO2 (0.40) LMNATSHRALOX12ACHECES2
Aniline SCHEMBL27368335 0.81 TSHR (0.48) LMNATSHRCYP2D6PARP1NPC1
Naphthalene SCHEMBL27608457 0.80 CYP2A6 (0.38) LMNATSHRALOX12CES2CES1
Acetophenone SCHEMBL28593300 0.80 HPGD (0.52) LMNATSHRCES2CES1CYP2D6
Toluene SCHEMBL1360632 0.79 LMNA (0.65) LMNATSHRALOX12ACHECES2
Benzene SCHEMBL27536972 0.79 CYP3A4 (0.35) LMNATSHRACHEPARP1L3MBTL1
Toluene SCHEMBL11518095 0.79 LMNA (0.65) LMNATSHRALOX12ACHECES2
Benzene SCHEMBL28203037 0.79 CYP3A4 (0.35) LMNATSHRACHEPARP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260084387-A1 Multilayer Piezoelectret Film Element, Polymeric Porous Sheet, and Method for Manufacturing the Same HUBEI XIANGYUAN HIGH TECH CO LTD (CN) 2026-03-26 — — US disclosed
EP-3640248-B1 AMINOPYRIMIDINE DERIVATIVES, PREPARATION METHOD THEREFOR AND USE THEREOF BEIJING ADAMADLE BIOTECHNOLOGY LLC (CN) 2023-08-23 — — EP disclosed
CN-114174269-B Pyrimidine compounds acting on EGFR and ERBB2 华润医药控股有限公司 2023-07-18 — — CN disclosed
US-11352352-B2 Aminopyrimidine compound, preparation method therefor and use thereof Beijing Adamadle Biotechnology Limited Liability Company (CN) 2022-06-07 — — US disclosed
CN-114469913-A Application of Tilorone in preventing/treating African swine fever virus infection 中国农业科学院哈尔滨兽医研究所（中国动物卫生与流行病学中心哈尔滨分中心） 2022-05-13 — — CN disclosed
CN-114174269-A Pyrimidines acting on EGFR and ERBB2 南京明德新药研发有限公司 2022-03-11 — — CN disclosed
CN-214075426-U Filtration extraction element of p-toluenesulfonylurea 吉安市海洲医药化工有限公司 2021-08-31 — — CN disclosed
CN-214075426-U Filtration extraction element of p-toluenesulfonylurea 吉安市海洲医药化工有限公司 2021-08-31 — — CN disclosed
CN-213376643-U P-toluenesulfonylurea synthesizer 吉安市海洲医药化工有限公司 2021-06-08 — — CN disclosed
CN-213376643-U P-toluenesulfonylurea synthesizer 吉安市海洲医药化工有限公司 2021-06-08 — — CN disclosed
CN-213266344-U Synthesis device of p-toluenesulfonylurea 吉安市海洲医药化工有限公司 2021-05-25 — — CN disclosed
CN-213266344-U Synthesis device of p-toluenesulfonylurea 吉安市海洲医药化工有限公司 2021-05-25 — — CN disclosed
CN-112121718-A A centrifugal agitating unit for toluene sulfonylurea 吉安市海洲医药化工有限公司 2020-12-25 — — CN disclosed
CN-112121718-A A centrifugal agitating unit for toluene sulfonylurea 吉安市海洲医药化工有限公司 2020-12-25 — — CN disclosed
EP-3640248-A1 AMINOPYRIMIDINE COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF Beijing Adamadle Biotechnology Limited Liability Company (CN) 2020-04-22 — — EP disclosed
US-20200087296-A1 AMINOPYRIMIDINE COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF Beijing Adamadle Biotechnology Limited Liability Company (CN) 2020-03-19 — — US disclosed
CN-107541197-B Intelligent water exploration type water plugging agent for high-temperature horizontal well 中国石油天然气股份有限公司 2020-02-14 — — CN disclosed
EP-0819765-A2 Reagent for measuring an amount of cholesterol WAKO PURE CHEMICAL INDUSTRIES, LTD (JP) 1998-01-21 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260084387-A1 Multilayer Piezoelectret Film Element, Polymeric Porous Sheet, and Method for Manufacturing the Same PIEZO1, MEF2D, TMEM63A LMNA 1299/4885TSHR 1302/4885ALOX12 4082/4885
US-20200087296-A1 AMINOPYRIMIDINE COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF WEE1, WEE2, EGFR LMNA 4594/4885TSHR 4187/4885ALOX12 826/4885
US-11352352-B2 Aminopyrimidine compound, preparation method therefor and use thereof WEE1, WEE2, EGFR LMNA 4594/4885TSHR 4187/4885ALOX12 826/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.