Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ATP4A | P20648 | 3/20 | 0.36 |
| ▸ | ATP4B | P51164 | 3/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.36 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29356666 | 0.75 | LOXL2 (0.51) | RAB9AMAPTKDM4ENPC1SMN1; SMN2 | |
| SCHEMBL13554406 | 0.74 | CYP3A4 (0.50) | MAPTKDM4ECHEK1CHEK2CYP3A4 | |
| SCHEMBL30646177 | 0.73 | LTA4H (0.39) | RAB9AMAPTKDM4ENPC1SMN1; SMN2 | |
| SCHEMBL8339774 | 0.72 | MAPT (0.52) | RAB9AMAPTKDM4EL3MBTL1RECQL | |
| SCHEMBL982041 | 0.72 | TSHR (0.32) | — | |
| SCHEMBL17713905 | 0.70 | KDM4E (0.76) | RAB9AMAPTKDM4ENPC1SMN1; SMN2 | |
| SCHEMBL14930515 | 0.69 | MCHR1 (0.51) | RAB9AMAPTKDM4ENPC1SMN1; SMN2 | |
| SCHEMBL22965412 | 0.69 | KDM4E (0.56) | MAPTKDM4ESMN1; SMN2L3MBTL1CHEK1 | |
| SCHEMBL14930473 | 0.69 | MCHR1 (0.51) | RAB9AMAPTKDM4ENPC1SMN1; SMN2 | |
| SCHEMBL7425025 | 0.68 | CYP3A4 (0.42) | MAPTKDM4ECHEK1CHEK2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105073745-A | Glucosylceramide synthase inhibitors | GENZYME CORP | 2015-11-18 | — | — | CN | disclosed |