Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | PLG | P00747 | 4/20 | 0.47 |
| ▸ | KLK1 | P06870 | 4/20 | 0.47 |
| ▸ | KLK6 | Q92876 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 4/20 | 0.45 |
| ▸ | CA2 | P00918 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 3/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MPO | P05164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28044791 | 0.86 | HIF1A (0.59) | RECQLHIF1ATSHRCYP2D6CA12 | |
| SCHEMBL28044798 | 0.81 | TSHR (0.50) | HIF1ATSHRCYP2D6CA12CA2 | |
| SCHEMBL28176619 | 0.80 | MEN1 (0.55) | RECQLCYP2D6MEN1KMT2AKDM4E | |
| SCHEMBL27733545 | 0.76 | RECQL (0.55) | RECQLTSHRCYP2D6LMNAHPGD | |
| SCHEMBL27913597 | 0.76 | MAPT (0.65) | HIF1ATSHRCYP2D6LMNAHPGD | |
| SCHEMBL28812675 | 0.73 | CA12 (0.68) | CYP2D6LMNACA12CA2CA9 | |
| SCHEMBL28044892 | 0.73 | PLG (0.47) | HIF1APLGKLK1KLK6KLKB1 | |
| SCHEMBL4783666 | 0.73 | TSHR (0.64) | HIF1ATSHRCYP2D6CA12CA2 | |
| SCHEMBL28044793 | 0.73 | PKM (0.63) | HIF1ATSHRCYP2D6LMNAHPGD | |
| SCHEMBL28890878 | 0.73 | HDAC1 (0.56) | RECQLCYP2D6LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105503642-B | N replaces 2 (2 hydroxybenzyl) glycyl amine compounds and its preparation and use | 湖南科技大学 | 2017-09-15 | — | — | CN | disclosed |
| CN-105503642-A | N-substituted-2-(2-hydroxybenzyl) glycine amide compound and preparing method and application thereof | UNIV HUNAN SCI & TECHNOLOGY | 2016-04-20 | — | — | CN | disclosed |