Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG | P00747 | 6/20 | 0.47 |
| ▸ | KLK1 | P06870 | 6/20 | 0.47 |
| ▸ | KLK6 | Q92876 | 6/20 | 0.47 |
| ▸ | BACE1 | P56817 | 2/20 | 0.46 |
| ▸ | RUVBL1 | Q9Y265 | 3/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | KLKB1 | P03952 | 3/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28044895 | 0.87 | HIF1A (0.50) | BACE1RUVBL1HDAC8HIF1ALTA4H | |
| SCHEMBL28176692 | 0.82 | KMT2A (0.49) | — | |
| SCHEMBL28044792 | 0.81 | NOS3 (0.45) | — | |
| SCHEMBL28044891 | 0.76 | TSHR (0.54) | — | |
| SCHEMBL28056446 | 0.73 | EGFR (0.52) | — | |
| SCHEMBL28044796 | 0.73 | RECQL (0.48) | PLGKLK1KLK6KLKB1HIF1A | |
| SCHEMBL2642980 | 0.73 | CA12 (0.57) | PLGKLK1KLK6 | |
| SCHEMBL16993871 | 0.73 | BACE1 (0.68) | BACE1HDAC8 | |
| SCHEMBL11880637 | 0.73 | BACE1 (0.68) | BACE1HDAC8 | |
| SCHEMBL28044789 | 0.72 | MEN1 (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105503642-B | N replaces 2 (2 hydroxybenzyl) glycyl amine compounds and its preparation and use | 湖南科技大学 | 2017-09-15 | — | — | CN | claimed |
| CN-105503642-A | N-substituted-2-(2-hydroxybenzyl) glycine amide compound and preparing method and application thereof | UNIV HUNAN SCI & TECHNOLOGY | 2016-04-20 | — | — | CN | claimed |
| CN-105503642-B | N replaces 2 (2 hydroxybenzyl) glycyl amine compounds and its preparation and use | 湖南科技大学 | 2017-09-15 | — | — | CN | disclosed |
| CN-105503642-A | N-substituted-2-(2-hydroxybenzyl) glycine amide compound and preparing method and application thereof | UNIV HUNAN SCI & TECHNOLOGY | 2016-04-20 | — | — | CN | disclosed |
| CN-105418531-A | 2-aryl-3-acylamino-1,3-benzoxazine compound and preparation and application thereof | UNIV HUNAN SCI & TECHNOLOGY | 2016-03-23 | — | — | CN | disclosed |