SCHEMBL2804480

SCHEMBL2804480

C=Cc1ncc2ccccc2n1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.42
GPR3 P46089 1/20 0.42
EGFR P00533 1/20 0.42
CYP1A2 P05177 6/20 0.40
ALDH1A1 P00352 2/20 0.39
MAPT P10636 2/20 0.39
GLA P06280 1/20 0.39
HPGD P15428 1/20 0.39
ACHE P22303 1/20 0.39
HTR3A P46098 1/20 0.39
HRH4 Q9H3N8 1/20 0.39
PDGFRB P09619 1/20 0.35
PDGFRA P16234 1/20 0.35
NCF1 P14598 1/20 0.34
NOS2 P35228 1/20 0.34
BACE1 P56817 1/20 0.34
CA12 O43570 1/20 0.34
CA9 Q16790 1/20 0.34
NPC1 O15118 2/20 0.34
MEN1 O00255 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31511445 1.00 KDM4E (0.42) KDM4EGPR3EGFRCYP1A2ALDH1A1
SCHEMBL1784501 0.83 KDM4E (0.45) KDM4EGPR3EGFRCYP1A2ALDH1A1
SCHEMBL4812818 0.79 CYP1A2 (0.42) KDM4EGPR3EGFRCYP1A2ALDH1A1
SCHEMBL2008080 0.79 KDM4E (0.42) KDM4EGPR3EGFRCYP1A2ALDH1A1
SCHEMBL6597825 0.79 KDM4E (0.42) KDM4EGPR3EGFRCYP1A2ALDH1A1
SCHEMBL27545204 0.79 KDM4E (0.42) KDM4EGPR3EGFRCYP1A2ALDH1A1
SCHEMBL27910297 0.78 KDM4E (0.41) KDM4EGPR3EGFRCYP1A2ALDH1A1
SCHEMBL6600134 0.76 PDGFRB (0.44) KDM4EGPR3EGFRCYP1A2ALDH1A1
SCHEMBL29784099 0.75 PDGFRB (0.56) KDM4EALDH1A1MAPTHPGDPDGFRB
SCHEMBL4498563 0.75 PDGFRB (0.56) KDM4EALDH1A1MAPTHPGDPDGFRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2760964-B1 AGGREGATING REAGENTS AND METHODS FOR MAKING AND USING SAME LUBRIZOL CORP (US) 2025-03-12 EP claimed
US-10202836-B2 Methods for fracturing formations using aggregating compositions THE LUBRIZOL CORPORATION (US) 2019-02-12 US claimed
US-20180016886-A1 METHODS FOR FRACTURING FORMATIONS USING AGGREGATING COMPOSITIONS THE LUBRIZOL CORPORATION 2018-01-18 US claimed
US-9550938-B2 Particulate aggregating and surface modification with improved hydrocarbon fluid flow through the aggregated particulates and over solid surface reagents and methods for making and using same Sumisaujana TCM Chemicals Sdn. Bhd. (MY) 2017-01-24 US claimed
US-20150152320-A1 PARTICULATE AGGREGATING AND SURFACE MODIFICATION WITH IMPROVED HYDROCARBON FLUID FLOW THROUGH THE AGGREGATED PARTICULATES AND OVER SOLID SURFACE REAGENTS AND METHODS FOR MAKING AND USING SAME Sumisaujana TCM Chemicals Sdn. Bhd. (MY) 2015-06-04 US claimed
US-20150114642-A1 AGGREGATING REAGENTS AND METHODS FOR MAKING AND USING SAME CLEARWATER INT LLC (US) 2015-04-30 US claimed
US-8944164-B2 Aggregating reagents and methods for making and using same CLEARWATER INTERNATIONAL LLC (US) 2015-02-03 US claimed
EP-2760964-A1 AGGREGATING REAGENTS AND METHODS FOR MAKING AND USING SAME Clearwater International, LLC (US) 2014-08-06 EP claimed
WO-2013046192-A1 AGGREGATING REAGENTS AND METHODS FOR MAKING AND USING SAME CLEARWATER INTERNATIONAL, L.L.C. (US) 2013-04-04 WO claimed
US-20130075100-A1 AGGREGATING REAGENTS AND METHODS FOR MAKING AND USING SAME CLEARWATER INTERNATIONAL, LLC (US) 2013-03-28 US claimed
US-12441823-B2 Resin composition for optical shaping KURARAY NORITAKE DENTAL INC. (JP) 2025-10-14 US disclosed
WO-2025126917-A1 DENTAL COMPOSITION クラレノリタケデンタル株式会社 2025-06-19 WO disclosed
EP-2760964-B1 AGGREGATING REAGENTS AND METHODS FOR MAKING AND USING SAME LUBRIZOL CORP (US) 2025-03-12 EP disclosed
CN-118159576-A Copolymer emulsion, and one-part thermosetting resin composition, two-part thermosetting resin composition, paint, resin cured film, and coating film using the copolymer emulsion 株式会社力森诺科 2024-06-07 CN disclosed
EP-3900693-B1 USE OF A RESIN COMPOSITION KURARAY NORITAKE DENTAL INC (JP) 2024-03-20 EP disclosed
US-7056600-B2 Layer configuration comprising an electron-blocking element AGFA GEVAERT (BE) 2006-06-06 US disclosed
WO-2004019348-A1 LAYER CONFIGURATION COMPRISING AN ELECTRON-BLOCKING ELEMENT AGFA-GEVAERT (BE) 2004-03-04 WO disclosed
US-20040040594-A1 Layer configuration comprising an electron-blocking element AGFA-GEVAERT (BE) 2004-03-04 US disclosed
US-20040044214-A1 Layer configuration comprising an electron-blocking element AGFA-GEVAERT (BE) 2004-03-04 US disclosed
WO-2004019346-A1 LAYER CONFIGURATION COMPRISING AN ELECTRON-BLOCKING ELEMENT AGFA-GEVAERT (BE) 2004-03-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040044214-A1 Layer configuration comprising an electron-blocking element PCBP1, RER1, SCO2 KDM4E 1362/4885GPR3 2459/4885EGFR 1464/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.