Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GPR3 | P46089 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.39 |
| ▸ | ERN1 | O75460 | 1/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.35 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.35 |
| ▸ | MGAM | O43451 | 1/20 | 0.35 |
| ▸ | FDPS | P14324 | 1/20 | 0.35 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.35 |
| ▸ | NCF1 | P14598 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27910297 | 0.98 | KDM4E (0.41) | KDM4EGPR3EGFRALDH1A1GAA | |
| Formic Acid SCHEMBL7099139 | 0.94 | ERN1 (0.39) | KDM4EGPR3EGFRALDH1A1GAA | |
| SCHEMBL1784501 | 0.83 | KDM4E (0.45) | KDM4EGPR3EGFRALDH1A1CYP1A2 | |
| SCHEMBL2804480 | 0.79 | KDM4E (0.42) | KDM4EGPR3EGFRALDH1A1CYP1A2 | |
| SCHEMBL27545204 | 0.79 | KDM4E (0.42) | KDM4EGPR3EGFRALDH1A1CYP1A2 | |
| SCHEMBL4812818 | 0.79 | CYP1A2 (0.42) | KDM4EGPR3EGFRALDH1A1CYP1A2 | |
| SCHEMBL6597825 | 0.79 | KDM4E (0.42) | KDM4EGPR3EGFRALDH1A1GAA | |
| SCHEMBL31511445 | 0.79 | KDM4E (0.42) | KDM4EGPR3EGFRALDH1A1CYP1A2 | |
| SCHEMBL30759006 | 0.76 | CYP2A6 (0.40) | KDM4EALDH1A1MAPTERN1 | |
| SCHEMBL11767773 | 0.76 | ALDH1A1 (0.43) | KDM4EALDH1A1MAPTERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 131 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114853729-B | Quinazoline-2-ketone compound and preparation method and application thereof | 汕头大学医学院 | 2024-03-29 | — | — | CN | claimed |
| CN-108884044-A | PIPERIDINE DERIVATIVE | 大塚制药株式会社 | 2018-11-23 | — | — | CN | claimed |
| CN-107001332-A | New piperidine derivative | 豪夫迈·罗氏有限公司 | 2017-08-01 | — | — | CN | claimed |
| CN-103201270-B | P2x4 receptor antagonist | NIPPON CHEMIPHAR CO | 2015-06-24 | — | — | CN | claimed |
| CN-102060786-A | 4-(substituted-1,3-diyne)-4-(trifluoromethyl)-3,4-dihydro substituted quinazoline-2-ketone compound as well as preparation method and application thereof | UNIV TIANJIN | 2011-05-18 | — | — | CN | claimed |
| US-7459415-B1 | Lubricant for thin film storage media | SEAGATE TECHNOLOGY LLC (US) | 2008-12-02 | — | — | US | claimed |
| US-20030199694-A1 | Thermally stable trimetrexates and processes for producing the same | MEDIMMUNE ONCOLOGY, INC. | 2003-10-23 | — | — | US | claimed |
| US-20030138670-A1 | Lubricant for thin film storage media | SEAGATE TECHNOLOGY LLC | 2003-07-24 | — | — | US | claimed |
| US-20020107393-A1 | Tremextrexate derivatives and pharmaceutical compositions comprising the same | MEDIMMUNE ONCOLOGY, INC. | 2002-08-08 | — | — | US | claimed |
| EP-1080079-A4 | THERMALLY STABLE TRIMETREXATES AND PROCESSES FOR PRODUCING THE SAME | US BIOSCIENCE (US) | 2001-10-04 | — | — | EP | claimed |
| US-6258952-B1 | CRYSTALLIZATION | MEDIMMUNE ONCOLOGY, INC. | 2001-07-10 | — | — | US | claimed |
| EP-1080079-A1 | THERMALLY STABLE TRIMETREXATES AND PROCESSES FOR PRODUCING THE SAME | U.S. BIOSCIENCE, INC. (US) | 2001-03-07 | — | — | EP | claimed |
| WO-1999059981-A1 | THERMALLY STABLE TRIMETREXATES AND PROCESSES FOR PRODUCING THE SAME | U.S. BIOSCIENCE, INC. (US) | 1999-11-25 | — | — | WO | claimed |
| US-12616653-B2 | Solid orodispersible pharmaceutical composition in film containing lorazepam | ALTERGON S.A. (CH) | 2026-05-05 | — | — | US | disclosed |
| EP-4573095-A1 | PYRIDOPYRIMIDINE KRAS INHIBITORS | Treeline Biosciences, Inc. (US) | 2025-06-25 | — | — | EP | disclosed |
| EP-4511128-A1 | MACROCYCLIC HETEROCYCLES AND USES THEREOF | Kumquat Biosciences Inc. (US) | 2025-02-26 | — | — | EP | disclosed |
| US-4248873-A | Nitro-substituted 1,4-dihydropyridines, processes for _their production and their medicinal use | BAYER AKTIENGESELLSCHAFT (DE) | 1981-02-03 | — | — | US | disclosed |
| EP-0012180-A1 | 1,4-Dihydropyridine compounds, their preparation, pharmaceutical compositions containing said compounds and preparation of these compositions | BAYER AG (DE) | 1980-06-25 | — | — | EP | disclosed |
| US-4179500-A | 1,4-Dihydropyridine-sugar derivatives, and their use as medicaments | BAYER AKTIENGESELLSCHAFT (DE) | 1979-12-18 | — | — | US | disclosed |
| EP-0001769-A1 | Sulfur-containing esters of 1,4-dihydropyridine carboxylic acids, their preparation and pharmaceutical use | BAYER AG (DE) | 1979-05-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12616653-B2 | Solid orodispersible pharmaceutical composition in film containing lorazepam | SIGMAR1, OPRD1, GABRE | KDM4E 2261/4885GPR3 1975/4885EGFR 4784/4885 |
| US-20030199694-A1 | Thermally stable trimetrexates and processes for producing the same | TYMS, TYMP, TOP1 | KDM4E 661/4885GPR3 3219/4885EGFR 4373/4885 |
| US-20020107393-A1 | Tremextrexate derivatives and pharmaceutical compositions comprising the same | TYMP, TYMS, DTYMK | KDM4E 673/4885GPR3 730/4885EGFR 2127/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.