Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | KRAS | P01116 | 1/20 | 0.44 |
| ▸ | MPO | P05164 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31160335 | 0.83 | KDM4E (0.61) | ALDH1A1KDM4EKRASMPOKMT2A | |
| SCHEMBL28044712 | 0.83 | KDM4E (0.61) | ALDH1A1KDM4EKRASMPOKMT2A | |
| Furfural SCHEMBL3040274 | 0.70 | ALDH1A1 (0.78) | ALDH1A1KDM4EKMT2AMAPTTDP1 | |
| SCHEMBL16156819 | 0.68 | HDAC6 (0.73) | KDM4EKMT2AMAPTLMNAGAA | |
| Furfural SCHEMBL790856 | 0.68 | ALDH1A1 (0.82) | ALDH1A1KDM4EKMT2AMAPTSMN1; SMN2 | |
| Furfural SCHEMBL17671277 | 0.68 | ALDH1A1 (0.82) | ALDH1A1KDM4EKMT2AMAPTTDP1 | |
| Furfural SCHEMBL27854764 | 0.68 | — | — | |
| Furfural SCHEMBL626705 | 0.68 | ALDH1A1 (1.00) | ALDH1A1KDM4EKMT2AMAPTSMN1; SMN2 | |
| Furfural SCHEMBL10811266 | 0.68 | ALDH1A1 (1.00) | ALDH1A1KDM4EKMT2AMAPTSMN1; SMN2 | |
| Furfural SCHEMBL20439 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105175312-A | 1-substituted-2-(carbazole-9-yl-acetic acid)-hydrazide Schiff base and preparation method thereof | UNIV SHAANXI SCIENCE & TECH | 2015-12-23 | — | — | CN | disclosed |