Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.61 |
| ▸ | MPO | P05164 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.53 |
| ▸ | MMP2 | P08253 | 1/20 | 0.52 |
| ▸ | KRAS | P01116 | 1/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | TSPO | P30536 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.49 |
| ▸ | FABP3 | P05413 | 1/20 | 0.49 |
| ▸ | FABP4 | P15090 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31160335 | 1.00 | KDM4E (0.61) | KDM4EMPOKMT2AHDAC6MMP2 | |
| Furfural SCHEMBL28044818 | 0.83 | ALDH1A1 (0.46) | KDM4EMPOKMT2AHDAC6MMP2 | |
| SCHEMBL16156819 | 0.82 | HDAC6 (0.73) | KDM4EKMT2AHDAC6PLA2G2AHDAC1 | |
| SCHEMBL3318685 | 0.79 | KDM4E (0.62) | KDM4EMPOKMT2AGLAALDH1A1 | |
| SCHEMBL3322075 | 0.79 | KDM4E (0.68) | KDM4EHDAC6GLATSPOPOLB | |
| SCHEMBL14003751 | 0.78 | KDM4E (0.73) | KDM4EHDAC6GLATSPOPOLB | |
| SCHEMBL14003754 | 0.78 | KDM4E (0.73) | KDM4EHDAC6GLATSPOPOLB | |
| SCHEMBL150053 | 0.76 | KDM4E (1.00) | KDM4EKMT2AGLATSPOALDH1A1 | |
| SCHEMBL29859932 | 0.76 | KDM4E (1.00) | KDM4EKMT2AGLATSPOALDH1A1 | |
| SCHEMBL31160384 | 0.76 | KDM4E (0.59) | KDM4EHDAC6KRASGLATSPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105175312-A | 1-substituted-2-(carbazole-9-yl-acetic acid)-hydrazide Schiff base and preparation method thereof | UNIV SHAANXI SCIENCE & TECH | 2015-12-23 | — | — | CN | claimed |
| CN-105732476-A | Carbazole-isatin type compound and preparation method and application thereof | 吉首大学 | 2016-07-06 | — | — | CN | disclosed |
| CN-105175312-A | 1-substituted-2-(carbazole-9-yl-acetic acid)-hydrazide Schiff base and preparation method thereof | UNIV SHAANXI SCIENCE & TECH | 2015-12-23 | — | — | CN | disclosed |
| CN-105175312-A | 1-substituted-2-(carbazole-9-yl-acetic acid)-hydrazide Schiff base and preparation method thereof | UNIV SHAANXI SCIENCE & TECH | 2015-12-23 | — | — | CN | disclosed |