Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.84 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.84 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.78 |
| ▸ | RAB9A | P51151 | 2/20 | 0.78 |
| ▸ | POLB | P06746 | 2/20 | 0.78 |
| ▸ | NPC1 | O15118 | 1/20 | 0.78 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.78 |
| ▸ | GAA | P10253 | 1/20 | 0.78 |
| ▸ | HTT | P42858 | 3/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.68 |
| ▸ | MEN1 | O00255 | 3/20 | 0.66 |
| ▸ | LMNA | P02545 | 2/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.66 |
| ▸ | PPARG | P37231 | 2/20 | 0.66 |
| ▸ | TP53 | P04637 | 2/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.66 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.66 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.66 |
| ▸ | PKM | P14618 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8310013 | 0.91 | MAPT (0.80) | MAPTKMT2ASMN1; SMN2RAB9APOLB | |
| SCHEMBL12443211 | 0.90 | MAPT (0.74) | MAPTKMT2ASMN1; SMN2RAB9APOLB | |
| SCHEMBL12443223 | 0.88 | MAPT (0.71) | MAPTKMT2ASMN1; SMN2RAB9APOLB | |
| SCHEMBL9423772 | 0.88 | MAPT (0.75) | MAPTKMT2ASMN1; SMN2RAB9APOLB | |
| SCHEMBL7130609 | 0.88 | RORC (0.84) | MAPTKMT2ASMN1; SMN2RAB9APOLB | |
| SCHEMBL25393198 | 0.88 | MAPT (0.70) | MAPTKMT2ASMN1; SMN2RAB9APOLB | |
| SCHEMBL12443206 | 0.86 | MAPT (0.73) | MAPTKMT2ASMN1; SMN2RAB9APOLB | |
| SCHEMBL12443207 | 0.86 | MAPT (0.73) | MAPTKMT2ASMN1; SMN2RAB9APOLB | |
| SCHEMBL25394310 | 0.85 | MAPT (0.71) | MAPTKMT2ASMN1; SMN2RAB9APOLB | |
| SCHEMBL28010009 | 0.85 | KMT2A (0.74) | MAPTKMT2ASMN1; SMN2RAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105294473-A | 2-chlorine-4,4'-diaminobenzanilide preparation method | CHANGZHOU SUNLIGHT PHARM CO LTD | 2016-02-03 | — | — | CN | disclosed |