Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.80 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.80 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.80 |
| ▸ | MEN1 | O00255 | 3/20 | 0.80 |
| ▸ | TP53 | P04637 | 2/20 | 0.80 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.80 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.80 |
| ▸ | PPARG | P37231 | 2/20 | 0.80 |
| ▸ | LMNA | P02545 | 1/20 | 0.80 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.80 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.80 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.80 |
| ▸ | PKM | P14618 | 1/20 | 0.80 |
| ▸ | TSHR | P16473 | 1/20 | 0.80 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.80 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.80 |
| ▸ | THPO | P40225 | 1/20 | 0.80 |
| ▸ | MTOR | P42345 | 1/20 | 0.80 |
| ▸ | RORC | P51449 | 1/20 | 0.80 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.80 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28044831 | 0.91 | MAPT (0.84) | MAPTSMN1; SMN2KMT2AMEN1TP53 | |
| SCHEMBL29369092 | 0.89 | RORC (1.00) | MAPTSMN1; SMN2KMT2AMEN1TP53 | |
| SCHEMBL420231 | 0.89 | RORC (1.00) | MAPTSMN1; SMN2KMT2AMEN1TP53 | |
| SCHEMBL12443223 | 0.86 | MAPT (0.71) | MAPTSMN1; SMN2KMT2AMEN1TP53 | |
| SCHEMBL12443211 | 0.84 | MAPT (0.74) | MAPTSMN1; SMN2KMT2AMEN1TP53 | |
| SCHEMBL3340347 | 0.84 | KMT2A (0.69) | MAPTSMN1; SMN2KMT2AMEN1TP53 | |
| SCHEMBL10836873 | 0.84 | KMT2A (0.72) | MAPTSMN1; SMN2KMT2AMEN1TP53 | |
| SCHEMBL6565993 | 0.84 | KMT2A (0.68) | MAPTSMN1; SMN2KMT2AMEN1TP53 | |
| SCHEMBL28489220 | 0.83 | KMT2A (0.67) | MAPTSMN1; SMN2KMT2AMEN1TP53 | |
| SCHEMBL9423772 | 0.83 | MAPT (0.75) | MAPTSMN1; SMN2KMT2AMEN1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104428289-B | As the triazole compounds of antivirotic | 弗·哈夫曼-拉罗切有限公司 | 2017-06-23 | — | — | CN | disclosed |
| CN-104428289-A | Triazole compounds as antivirals | HOFFMANN LA ROCHE | 2015-03-18 | — | — | CN | disclosed |
| EP-0790986-B1 | ANILINE DERIVATIVES | ZENECA LTD (GB) | 1999-01-20 | — | — | EP | disclosed |
| US-5821246-A | USEFUL AS TYROSINE KINASE INHIBITORS AND FOR THE TREATMENT OF PROLIFERATIVE DISEASES SUCH AS CANCER | ZENECA LIMITED (GB) | 1998-10-13 | — | — | US | disclosed |
| EP-0790986-A1 | ANILINE DERIVATIVES | ZENECA LIMITED (GB) | 1997-08-27 | — | — | EP | disclosed |
| WO-1996015118-A1 | ANILINE DERIVATIVES | ZENECA LIMITED (GB) | 1996-05-23 | — | — | WO | disclosed |