SCHEMBL28044851

SCHEMBL28044851

NCO[Si](O)(O)Oc1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 2/20 0.39
MAOB P27338 3/20 0.38
AOC2 O75106 2/20 0.38
MAOA P21397 2/20 0.38
DAO P14920 1/20 0.38
LTA4H P09960 3/20 0.36
LOXL2 Q9Y4K0 4/20 0.36
LOX P28300 1/20 0.35
ALDH1A1 P00352 1/20 0.34
RECQL P46063 1/20 0.34
AOC3 Q16853 3/20 0.34
PLA2G2A P14555 1/20 0.34
CYP2A6 P11509 1/20 0.33
HTR2A P28223 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
TSHR P16473 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL896125 0.79 LTA4H (0.45) TAAR1MAOALTA4HALDH1A1RECQL
SCHEMBL10458474 0.79 LTA4H (0.41) MAOBAOC2MAOADAOLTA4H
SCHEMBL27905791 0.75 CYP3A4 (0.38) ALDH1A1SMN1; SMN2TSHR
SCHEMBL28267970 0.74 TAAR1 (0.32) TAAR1
SCHEMBL1217901 0.74 LTA4H (0.45) TAAR1MAOALTA4HALDH1A1RECQL
SCHEMBL5801997 0.73 LTA4H (0.50) MAOALTA4HALDH1A1RECQLHTR2A
Fluoride SCHEMBL27845931 0.72 LTA4H (0.43) MAOALTA4HALDH1A1RECQLTSHR
SCHEMBL27746358 0.71 CA4 (0.46) LTA4HALDH1A1RECQLSMN1; SMN2TSHR
SCHEMBL28409417 0.69 TSHR (0.61) TAAR1ALDH1A1AOC3HTR2ASMN1; SMN2
SCHEMBL8128268 0.69 CA4 (0.48) TAAR1MAOBMAOALTA4HALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105175451-B The preparation method of double (phosphine heterocyclic methyl) ester compounds of aminomethyl phenyl silicic acid 苏州科技大学 2017-12-01 CN claimed
CN-105175451-A Method for preparing methylphenyl silicic acid bis(phosphorous heterocyclic methyl) ester compound USTC UNIV SCIENCE TECH CN 2015-12-23 CN claimed
CN-107987680-A Water-base epoxy graphene anticorrosive paint 海洋化工研究院有限公司 2018-05-04 CN disclosed
CN-105175451-B The preparation method of double (phosphine heterocyclic methyl) ester compounds of aminomethyl phenyl silicic acid 苏州科技大学 2017-12-01 CN disclosed
CN-105175451-B The preparation method of double (phosphine heterocyclic methyl) ester compounds of aminomethyl phenyl silicic acid 苏州科技大学 2017-12-01 CN disclosed
CN-105175451-B The preparation method of double (phosphine heterocyclic methyl) ester compounds of aminomethyl phenyl silicic acid 苏州科技大学 2017-12-01 CN disclosed
CN-105175451-A Method for preparing methylphenyl silicic acid bis(phosphorous heterocyclic methyl) ester compound USTC UNIV SCIENCE TECH CN 2015-12-23 CN disclosed